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National Academy of Sciences

Paired Ends: Apr 28, 2009

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Hagan Bayley, Detlef Weigel, Todd Smith, Michael Sadowsky, Catalina Lopez-Correa, Garry Merry

By integrating new and published data on CD34+ human stem-progenitor cell transcripts, a team of American researchers have mapped a transcriptome that may offer insights into the process of blood system development.

Obama said that the US is in danger of slipping from its lead spot in science innovation and called for "a historic investment" in research and education that would fuel innovation as the GI Bill did a half-century ago.

News about Sonny Perdue, Elias Zerhouni, Rick Jory, Jack Wheeler, Richard Duke, Joe Bagan Chris Clement, Dick Hinson, Jim Kasic, Carin Kutcipal, Mark Lupa, Frank Ronchetti, John Foster, Marco Baccanti

Papers of Note: Apr 16, 2009

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RNAi-related papers published in March 2009.

The data demonstrate that siRNAs that are 21 nucleotides in length or longer suppress both hemangiogenesis and lymphangiogenesis in vivo, regardless of their targets or sequences, due to the activation of TLR3.

Using microarray and Northern blot analyses, Johns Hopkins University researchers discovered that the levels of almost all miRNAs increases following cell-cell contact in Drosophila and mammalian cell lines, regardless of whether these cells display contact inhibition.

A group of Atlanta researchers used a technique called desorption electrospray ionization mass spectrometry to help characterize antibacterial and antifungal compounds on the surface of a tropical red algae.

Based on comparisons between piRNA clusters in mouse, rat, and other mammalian genomes, University of Michigan researchers found evidence that piRNAs are likely under positive selection and capable of rapid expansion.

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Nebula Genomics will be auctioning George Church's genome as a nonfungible token, according to The Scientist.

Anthony Gregg, the outgoing president of the American College of Medical Genetics and Genomics, has resigned after using racially insensitive language. 

Facebook has developed an artificial intelligence approach to predict how drugs interact in cells, New Scientist reports.

In PNAS this week: adaptations among high-altitude Mycobacterium tuberculosis, response of multiple myeloma cells to chemotherapy-induced stress, and more.