Mount Sinai

Researchers from the Genetics Investigation of Anthropometric Traits consortium tied loci in lipid homeostasis and other pathways to differences in waist-to-hip ratio.

The researchers will combine genomic analysis with environmental and mobile device data from 1,200 participants to try to better understand the disease.

Researchers in the US and Europe are implementing pathogen sequencing surveillance programs to track infectious diseases within hospitals.

Epic Sciences will donate its No Cell Left Behind platform to the clinical trial, which will enroll about 1,000 patients over three years.

The program will be led by computational scientist Adam Margolin and focus on integrating large-scale data analysis and genomic technologies to speed drug discoveries.

Screening of disease-linked cell types might bolster drug discovery efforts in schizophrenia, according to a proof-of-concept study.

Counselors in Demand

Mount Sinai's Eric Schadt writes at Spectrum that genetic counselors help people cope with incidental genetic findings.

An analysis of post-mortem brain transcripts led to Alzheimer's-related alternative gene splicing and expression events, including those influenced by known risk alleles.

In urothelial cancer, the presence of a gene signature stemming from stromal cells seemed to interfere with anti-PD-1 drug response in tumors with infiltrating T-cells.

The groups will conduct a study evaluating the benefits of targeted next-generation sequencing in the diagnosis and care of infants with genetic disorders.

Pages

NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.

Researchers may experience the effects of the government shutdown for a while, the Los Angeles Times reports.

A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.

In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.