Mount Sinai People in the News at Veracyte, Invitae, Mount Sinai, InterVenn Biosciences, Applied BioCode, More Executive and academic appointments, promotions, and departures in omics and molecular diagnostics for the week of Sept. 25, 2023. HPV Tumor DNA Liquid Biopsy Test Shows Promise for Oropharyngeal Cancer Diagnosis, Surveillance Researchers studied the accuracy of a commercial HPV tumor DNA blood test in almost 400 patients with HPV-related oropharyngeal squamous cell carcinoma. Bipolar Disorder Research Initiative Awards $15M for Brain Genetics, Omics Platforms BD2, a collaboration between three family philanthropies and the Milken Institute, made the awards to two teams for large-scale sequencing and a brain atlas. Protein-Truncating Variants Confer Schizophrenia Risk Across Human Populations A recent study also found two new genes involved in schizophrenia risk that could become potential therapeutic targets. Linus Biotechnology Raises $16M in Series A Funding The Mount Sinai spinout will use the funds to advance its StrandDx platform, correlating environmental exposures to biological responses. Dec 22, 2022 Gene Signature Reflects Host Response to COVID-19 Infections With Low Cross-Reactivity Dec 9, 2022 Long COVID Clues Found in Acute SARS-CoV-2 Infection Blood Samples Sep 27, 2022 Neuropsychiatric Disease Clues Drawn From Enhancer Expression Analysis Aug 24, 2022 Mount Sinai Million Health Discoveries Program Represents New Ground for Partner Regeneron Premium Aug 17, 2022 Draft Human Pangenome Reference Shows the Way to Capturing More Human Diversity Premium Aug 12, 2022 Mount Sinai, Regeneron Launch Sequencing Project to Augment Genetics-Based Precision Medicine Jun 21, 2022 Mount Sinai Leveraging T-Cell-Based Technology to Determine Immune Response to SARS-CoV-2 Premium Jun 15, 2022 Blood-Based PD-L1 Tracking Could Offer Improved Response Prediction for Lung Cancer Immunotherapy Premium Jun 7, 2022 BioMark Diagnostics, Icahn Mount Sinai to Develop Multiomic Lung Cancer Tests Mar 29, 2022 Use of Community Resources to Inform Black Patients of Genetic Test Results Improves Outcomes, Study Finds Premium Mar 15, 2022 Structural Variants Influence Brain Gene Expression, Disease Risk Mar 8, 2022 Genetics of Cardiometabolic Traits Informed by Predicted Gene Expression Across Ancestries Feb 24, 2022 Researchers Look to New Sequencing Methods to Settle Debate Over 6mA Modifications in Humans Premium Jan 25, 2022 Pathogenic Variants in Disease-Causing Genes Have Low Penetrance on Average, Study Finds Jan 21, 2022 New Approach Identifies Candidate Causal Variants for Neuropsychiatric, Neurodevelopmental Conditions Nov 17, 2021 Multiple Myeloma Patient Similarity Network Reveals Prognostically Informative Subgroups Nov 16, 2021 Cancer Genomic Analysis Reveals Distinct Features in Tumors From Patients Under 50 Years Old Oct 27, 2021 Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger Premium Sep 28, 2021 Microbes Behind Successful Fecal Microbiota Transplantations May Become Basis for New Treatments Sep 7, 2021 Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis Load More Breaking News Verily Awarded CDC Contract for Wastewater Surveillance Genomic Health to Pay $32.5M to Resolve Cancer Test False Claims Allegations by DOJ Vela Diagnostics Inks Japan Distribution Agreement for HIV-1 Drug Resistance Tests Coronary Artery Calcification Contributors, Potential Drug Targets Found in Cross-Ancestry GWAS Max Planck Team Uses Spatial Single-Cell Proteomics Method to Analyze Hepatocyte Heterogeneity The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.