Mount Sinai
Multiple Myeloma Patient Similarity Network Reveals Prognostically Informative Subgroups
Researchers identified 12 multiple myeloma subgroups based on mutation, copy number, chromosomal rearrangement, and expression features in more than 650 tumors.
Cancer Genomic Analysis Reveals Distinct Features in Tumors From Patients Under 50 Years Old
Researchers saw distinct driver mutation, tumor microenvironment features, and more when they compared tumors from dozens of cancer types in patients younger or older than 50.
Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger
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Researchers have conflicting interpretations of recent studies into how much polygenic risk scores might contribute to disease risk predictions.
Microbes Behind Successful Fecal Microbiota Transplantations May Become Basis for New Treatments
With microbial sequencing data for FMT donors and recipients, researchers defined which bugs take up long-term residence in recipient guts.
Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis
The findings highlight the need for polygenic risk scores to not only be predictive but also provide additional information that cannot be captured elsewhere more easily.