modENCODE

NEW YORK (GenomeWeb) – A set of studies published online today in Nature offers a look at similarities and differences detected in the regulatory machinery over time and across organisms.

NEW YORK (GenomeWeb) – A set of studies published in Genome Research today outlines findings from the modENCODE project, an effort aimed at identifying and understanding regulatory elements in the genomes of fruit fly and Caenorhabditis elegans worm model organisms.

NHGRI's advisory council has agreed to expand ENCODE to study humans more deeply, and cleared a new $30 million gene regulation program.

Researchers with the "model organism Encyclopedia of DNA Elements" Consortium today described some initial findings from their functional studies of the Drosophila melanogaster and Caenorhabditis elegans genomes.

In Sequence recently spoke with Celniker, who heads the department of genome dynamics at Lawrence Berkeley National Laboratory, to find out what the modENCODE project has achieved at its halfway point, and what role new sequencing technologies are playing in it.

The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.