MMRC

Based on their whole-genome or exome analyses of multiple myeloma samples from 38 individuals, members of the Multiple Myeloma Research Consortium have learned more about known pathways contributing to the disease and identified several previously unidentified genetic players.

Researchers involved in the Multiple Myeloma Research Consortium Genomics Initiative reported on their initial sequence and copy number analyses of multiple myeloma genomes at the American Association for Cancer Research annual meeting this week.

The initiative, which involves the Broad Institute and the Translational Genomics Research Institute, aims to comprehensively analyze the genomes of 250 multiple myeloma samples. MMRF said this spring that as part of the project, the Broad would sequence the genomes of at least 50 of the tumors.