James Collins and Shimyn Slomovic have created a modular system that could help research in gene editing, chromosomal structure, and cancer.
By editing a promoter of an enhancer of the mutated hemoglobin responsible for sickle cell disease, the researchers may have found a way to treat it.
The researchers demonstrated the ability to use one Cas9 enzyme for both genome editing and activating gene expression in the same cell.
Using epigenetic data, expression profiles, gene editing, and more, researchers uncovered interactions in fat precursor cells that may explain FTO's role in obesity.
MIT researchers have developed genetic parts that can be used to program gene expression in the commensal gut bacterium Bacteroides thetaiotaomicron.
A report from MIT identifies areas of scientific research where declining research support is hindering needed advances.
The Cas9 enzyme from S. aureus can be delivered by a viral vector and could lead to more CRISPR-based research tools and novel study designs in animal models.
Genome editing technology could give researchers the ability to knock out individual species from microbiota and turn bacteria into detectors of antibiotic resistance.
NEW YORK (GenomeWeb) – In Nature Genetics, researchers from the Memorial Sloan Kettering Cancer Center and the University of Copenhagen described some of the common non-protein-coding mutations
NEW YORK (GenomeWeb) – Gut microbial communities are largely stable over time, though they can be shaped by host behaviors such as diet, according to a new sequencing-based analysis appearing in Genome Biology.
In PLOS this week: transcriptomic and genomic analysis of prostate cancer by ancestry, genes linked to liver function in Korean cohort, and more.
British Columbia is incorporating genomics into its tracking of the ongoing COVID-19 outbreak, Business in Vancouver reports.
An analysis by the Personalized Medicine Coalition finds that about a quarter of new drugs approved in 2019 by the US Food and Drug Administration were personalized medicines.
The governor of New York has proposed a five-year plan to study the genomes of people with or who are at high risk of developing Alzheimer's disease.