The method permits the detection of mRNA transcripts of interest for more than 6,000 single cells in parallel per assay with high sensitivity and specificity; and has a variety of applications, including detecting replicating intracellular pathogens such as retroviruses.
Foundation Medicine has raised $25 million in Series A financing that it will use to "broadly analyze the relevant tumor genomic and other molecular information in individual patients' cancers and connect it with a knowledgebase of clinical data to help oncologists personalize treatment."
As part of its request for dismissal, MIT admitted no wrongdoing, but agreed to be bound by any court ruling against the case's other defendants, the Whitehead Institute for Biomedical Research and the University of Massachusetts Medical School.
Using a synthetic gene expression system in yeast, Massachusetts Institute of Technology researchers demonstrated that promoter noise and transcription factor instability can prompt bimodal gene expression.
Using a morphological classifier and computational method for integrating this data with information from an RNA interference screen, a group of researchers from the Massachusetts Institute of Technology and Harvard University delved into genetic interactions affecting the Rho signaling pathway in Drosophila.