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The research team said its nanofluidic system increased the proportion of nucleic acid and protein disease biomarkers a billionfold prior to detection.

The grant recipients will receive up to $5 million each and are led by scientists at institutions including Harvard Medical School and the Cleveland Clinic.

In Nucleic Acids Research this week: approach to generate chromatin interaction networks, signature of cellular senescence, and more.

In PNAS this week: analysis of Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics study samples, chromosome loss and gain in prostate cancer, and more.

The Massachusetts Institute of Technology-led team uncovered cell-type-specific transcriptional changes that occur early on in disease development.

Eighteen researchers call for a temporary stop to all clinical uses of human germline editing in a piece appearing in Nature.

In Nature this week: machine learning-based method for CRISPR editing, symbiotic genes of Medicago truncatula, and more.

Using a mouse model of immunotherapy resistant disease, the researchers found that this program could be targeted by an inhibitor to improve response.

The MIT team found that a previously uncharacterized Cas9 from Streptococcus canis has fewer PAM requirements than the more widely used S. pyogenes Cas9.

Researchers describe a way to share data while keeping it secure, Agence France Presse reports.

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Holden Thorp is to be the new editor-in-chief of Science and its related journals.

A genetic analysis of salmon scales collected over the course of a century points to a sharp decline in the number of fish returning each year to river in British Columbia, CBC reports.

Adelaide University has suspended the head of an ancient DNA lab as its investigation of workplace bullying continues, Australia's ABC News reports.

In PNAS this week: gene expression profiles of adipocyte subtypes, computational approach for improving plant expressome analysis, and more.