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MIT Researchers Devise Oligo Barcode-Based 'File System' for DNA Data Storage
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The researchers have applied for a patent on their technology and have formed a startup, Cache DNA, to develop a low-cost platform for DNA storage and retrieval.

CRISPRoff Reversible Epigenome Editing Method Could Enable Safer, More Precise Therapeutics
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UCSF and MIT researchers have developed a way to edit the epigenome and then completely reverse the changes, when needed.

Human Epigenome Map Reveals New Insights Into Genetic Loci for Traits, Diseases

By bringing together epigenomic profiles for hundreds of tissue samples, researchers mapped regulatory modules relevant to a range of tissue and disease types.

Expansion Sequencing Improves on Church Lab's In Situ Transcriptomics Method
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Researchers have developed a higher-resolution in situ RNA sequencing method that relies on physically expanding a polymer network that holds the RNA.

Lung Cancer Metastasis Study Relies on CRISPR-Based Method to Track Single-Cell Lineages

Researchers traced the development of thousands of engineered human lung cancer cells within a mouse model of disease to examine metastasis.

Jan 11, 2021

Broad Institute, MIT Researchers Probe Genome Structure With New In Situ DNA Sequencing Method
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Oct 20, 2020

RNA Timestamps Method Clocks Age of Individual RNAs in Single-Cell Experiments
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Sep 24, 2020

Catalog DNA Merges Molecular Biology, Information Theory to Pursue DNA-Based Computing
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Sep 21, 2020

Malaria Assays Use CRISPR for Point-of-Care Multispecies Detection
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Jul 29, 2020

ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization

Jul 15, 2020

ReviveMed, Bristol Myers Squibb to Study Metabolomics for Cancer Immunotherapy

Jun 11, 2020

Coronavirus Pathogenicity Clues Uncovered Using Machine-Learning Approach

Apr 30, 2020

Prostate Cells With Regenerative Capability Uncovered by Single-Cell Transcriptomics

Apr 29, 2020

Broad Institute Researchers Develop Viral Detection Platform Based on Microfluidics, CRISPR Tech

Apr 16, 2020

Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions

Mar 5, 2020

Analysis of NatGeo Genographic Project Data Reveals Complexity of US Population

Feb 24, 2020

Ancient Salmonella Genomes Reveal Human Lifestyle-Related Host Adaptations

Jan 29, 2020

Breast Cancer Risk Clues Found By Sequencing Cells From BRCA2 Germline Mutation Carriers

Aug 22, 2019

Single-Base Editing Expands Possibilities for Computing With DNA in Cells

Jul 31, 2019

MIT Researchers Developing Amplification-Free 'Massively Parallel' Microfluidic Testing Platform
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Jul 24, 2019

Gray Foundation Awards $25M in Cancer Research Grants

May 1, 2019

Single-Cell Transcriptomic Study Maps Changes That Arise in Brain During Alzheimer's Disease

Nov 1, 2018

Immunotherapy Resistance in Melanoma Linked to Gene Expression Program

Oct 24, 2018

CRISPR Study Details Highly Flexible Cas9 Ortholog, SPAMALOT Pipeline for New Cas9 Discovery

Aug 22, 2018

Single-Cell Expression Analysis of Nasal Polyps Suggests Mechanisms of Chronic Inflammation

Breaking News
The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.