In PNAS this week: analysis of Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics study samples, chromosome loss and gain in prostate cancer, and more.
The Massachusetts Institute of Technology-led team uncovered cell-type-specific transcriptional changes that occur early on in disease development.
Eighteen researchers call for a temporary stop to all clinical uses of human germline editing in a piece appearing in Nature.
In Nature this week: machine learning-based method for CRISPR editing, symbiotic genes of Medicago truncatula, and more.
Using a mouse model of immunotherapy resistant disease, the researchers found that this program could be targeted by an inhibitor to improve response.
The MIT team found that a previously uncharacterized Cas9 from Streptococcus canis has fewer PAM requirements than the more widely used S. pyogenes Cas9.
Researchers describe a way to share data while keeping it secure, Agence France Presse reports.
The researchers found that the diversity of epithelial cell types was reduced in nasal polyps, which contained few glandular and ciliated cells and were enriched in basal cells.
In PNAS this week: targeting recurrent IDH1 and IDH2 mutations in gliomas, silkworms genetically modified to produce spider silk, and more.
In Nature this week: expansion of disease-resistance genes among long-lived oak trees, and more.
The Hill reports President Donald Trump issued an executive directing federal agencies to cut the number of board and advisory committees they have.
Scientists in Canada are looking to the UK's plan to sequence children with rare conditions for inspiration, the National Post reports.
The New York Times reports that researchers are combining tools to more quickly develop crops to feed a growing population and cope with shifting climates.
In PNAS this week: copy number changes arose during polar bear evolution, genomic and transcriptomic analysis of the Siberian hamster, and more.