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In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.

Built on concepts developed in Timothy Lu's MIT lab, a new approach to DNA-based computing in a cell increases precision and, potentially, scale.

The research team said its nanofluidic system increased the proportion of nucleic acid and protein disease biomarkers a billionfold prior to detection.

The grant recipients will receive up to $5 million each and are led by scientists at institutions including Harvard Medical School and the Cleveland Clinic.

In Nucleic Acids Research this week: approach to generate chromatin interaction networks, signature of cellular senescence, and more.

In PNAS this week: analysis of Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics study samples, chromosome loss and gain in prostate cancer, and more.

The Massachusetts Institute of Technology-led team uncovered cell-type-specific transcriptional changes that occur early on in disease development.

Eighteen researchers call for a temporary stop to all clinical uses of human germline editing in a piece appearing in Nature.

In Nature this week: machine learning-based method for CRISPR editing, symbiotic genes of Medicago truncatula, and more.

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A South African university has told the Wellcome Sanger Institute to return DNA samples it has from indigenous African communities, The Times reports.

The University of California, Berkeley's Rasmus Nielsen and Xinzhu Wei have retracted their CCR5 gene paper due to a technical artifact.

 

University of Virginia researchers are exploring a genetic risk test to gauge type 1 diabetes risk, NPR reports.

In PNAS this week: researchers compare two high-grade neuroendocrine lung cancers, height among ancient Europeans, and more.