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Researchers traced the development of thousands of engineered human lung cancer cells within a mouse model of disease to examine metastasis.

The method, published in Science, pairs in situ sequencing with NGS using barcodes to provide spatial information on DNA sequences inside tissues.

In PNAS this week: study of gene mutation implicated in deafness, examination of codon origins, and more.

In Genome Research this week: assay for profiling chromatin accessibility, analysis of genetic variants among malaria-transmitting mosquitoes, and more.

Researchers from the Broad Institute and MIT have used RNA editing and single-cell RNA sequencing to record when RNA molecules were transcribed.

The Boston-based firm is pursuing nanopore technology as a readout for its unique information-encoding format, which could help customers store vast amounts of data.

The diagnostics are capable of detecting fewer than two parasites per microliter of blood and would cost an estimated $.61 per test.

In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.

Their Own Guinea Pigs

Technology Review reports some researchers are trying homemade SARS-CoV-2 vaccines on themselves.

In more than a dozen new papers, ENCODE researchers reported on analyses of the human and mouse genomes, using new data types and additional tissues.

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Politico notes that the Biden Administration has not yet nominated a permanent Food and Drug Administration commissioner. 

Anthony Fauci also informed the World Health Organization executive board that the US would be joining the COVAX initiative, according to CNBC.

A new preprint suggests some SARS-CoV-2 variants could affect the effectiveness of current vaccines, the Associated Press reports.

In Nature this week: Australian lungfish provides details on the movement of vertebrate life from water to land, and more.