MIT MIT Researchers Devise Oligo Barcode-Based 'File System' for DNA Data Storage Premium The researchers have applied for a patent on their technology and have formed a startup, Cache DNA, to develop a low-cost platform for DNA storage and retrieval. CRISPRoff Reversible Epigenome Editing Method Could Enable Safer, More Precise Therapeutics Premium UCSF and MIT researchers have developed a way to edit the epigenome and then completely reverse the changes, when needed. Human Epigenome Map Reveals New Insights Into Genetic Loci for Traits, Diseases By bringing together epigenomic profiles for hundreds of tissue samples, researchers mapped regulatory modules relevant to a range of tissue and disease types. Expansion Sequencing Improves on Church Lab's In Situ Transcriptomics Method Premium Researchers have developed a higher-resolution in situ RNA sequencing method that relies on physically expanding a polymer network that holds the RNA. Lung Cancer Metastasis Study Relies on CRISPR-Based Method to Track Single-Cell Lineages Researchers traced the development of thousands of engineered human lung cancer cells within a mouse model of disease to examine metastasis. Jan 11, 2021 Broad Institute, MIT Researchers Probe Genome Structure With New In Situ DNA Sequencing Method Premium Oct 20, 2020 RNA Timestamps Method Clocks Age of Individual RNAs in Single-Cell Experiments Premium Sep 24, 2020 Catalog DNA Merges Molecular Biology, Information Theory to Pursue DNA-Based Computing Premium Sep 21, 2020 Malaria Assays Use CRISPR for Point-of-Care Multispecies Detection Premium Jul 29, 2020 ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization Jul 15, 2020 ReviveMed, Bristol Myers Squibb to Study Metabolomics for Cancer Immunotherapy Jun 11, 2020 Coronavirus Pathogenicity Clues Uncovered Using Machine-Learning Approach Apr 30, 2020 Prostate Cells With Regenerative Capability Uncovered by Single-Cell Transcriptomics Apr 29, 2020 Broad Institute Researchers Develop Viral Detection Platform Based on Microfluidics, CRISPR Tech Apr 16, 2020 Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions Mar 5, 2020 Analysis of NatGeo Genographic Project Data Reveals Complexity of US Population Feb 24, 2020 Ancient Salmonella Genomes Reveal Human Lifestyle-Related Host Adaptations Jan 29, 2020 Breast Cancer Risk Clues Found By Sequencing Cells From BRCA2 Germline Mutation Carriers Aug 22, 2019 Single-Base Editing Expands Possibilities for Computing With DNA in Cells Jul 31, 2019 MIT Researchers Developing Amplification-Free 'Massively Parallel' Microfluidic Testing Platform Premium Jul 24, 2019 Gray Foundation Awards $25M in Cancer Research Grants May 1, 2019 Single-Cell Transcriptomic Study Maps Changes That Arise in Brain During Alzheimer's Disease Nov 1, 2018 Immunotherapy Resistance in Melanoma Linked to Gene Expression Program Oct 24, 2018 CRISPR Study Details Highly Flexible Cas9 Ortholog, SPAMALOT Pipeline for New Cas9 Discovery Aug 22, 2018 Single-Cell Expression Analysis of Nasal Polyps Suggests Mechanisms of Chronic Inflammation Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.