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The hospital believes it is the first to receive approval from the state to use the instrument for diagnosing gene mutations.

Wendel and colleagues used a short hairpin library screen to identify genes whose knockdown mimicked the effect of microRNA-19, a member of the oncogenic miR-17-92 cluster, in lymphocytes, hypothesizing that this would reveal the genes responsible for the miRNA's activity.

The Institute for Systems Biology and MD Anderson Cancer Center are two of six research institutions selected as TCGA Genome Data Analysis Centers.

Under the Phenotypic Drug Discovery program, researchers from academia or biotech submit candidate compounds in specific therapeutic areas for Lilly to evaluate and profile. Participating organizations retain full IP rights to the compounds, but Lilly receives first rights to negotiate a broader collaboration or licensing agreement.

A group of researchers from Israel and the US report that they have characterized chromosomal abnormalities in different colorectal cancer stages and identified alterations associated with poor outcomes.

Both the project and the service are designed to offer cancer patients detailed information about their tumor at a timescale that can help their physicians tailor treatments. However, some experts say the results will not benefit many patients today.

Short Reads: Feb 3, 2009

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Broad Institute, Expression Analysis, Helicos BioSciences, University of Texas at Austin, Applied Biosystems, University of Georgia, ABRF, Genomatix, Illumina, Mondobiotech, 23andMe, Kapa Biosystems

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NPR reports that the patient who underwent a CRISPR-based treatment for sickle cell disease is doing well.

Resistance to ash dieback disease among some UK ash trees appears polygenic, the Independent reports.

In Nucleic Acids Research this week: sequencing strategy for flash-frozen brain tissue bank samples, new version of ChlamDB, and more.

A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.