Memorial Sloan-Kettering PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more. Gastric Cancer Cases Frequently Harbor Genetic Risk Variants, Suggesting Germline Testing Using panel sequence data for more than 500 esophagogastric cancer cases, researchers found pathogenic or likely pathogenic variants in almost 20 percent of those with gastric cancers. AACR Presentations Highlight Power of Large Tumor Atlases in Studies of Cancer Progression Premium The talks focused on studies stemming from the Cancer Moonshot initiative's Human Tumor Atlas Network project, which is readying its first data release. Science Reviews How Non-Genetic DNA Features Expand Utility of Liquid Biopsies, Presents Study of Enzymes in DNA Methylation In Science this week: review discusses advances in liquid biopsies, and more. Genome Sequencing Identifies Myeloma Precursor Disease With High Progression Risk Investigators flagged a set of myeloma-defining genomic events that marked precursor conditions that were prone to morph into multiple myeloma. Nov 24, 2020 Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves Premium Nov 18, 2020 MSK Study Suggests Germline Tests May Miss Mosaic Cancer Risk Mutations in Some Patients Premium Oct 29, 2020 Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies Oct 27, 2020 Clonal Hematopoiesis Mutation Study Reveals Risk of Treatment-Related Cancer Oct 7, 2020 Immunotherapy Response Prediction Improved by Baseline, On-Treatment Biomarker Combo Premium Sep 18, 2020 MSK Clonal Hematopoiesis Clinic Aims to Drive New Strategies for Cancer Risk Assessment, Prevention Premium Sep 17, 2020 New York City Opening Dedicated COVID-19 Testing Laboratory Sep 10, 2020 Epic Sciences, MSK Identify Potential Prostate Cancer Therapy Response Biomarker Premium Sep 4, 2020 Mutations in FOXA1 Gene Can Affect Breast Cancer Patients' Response to Therapy Jul 1, 2020 Polygenic Risk Score Modifies Breast Cancer Risk in Pathogenic Variant Carriers Jun 11, 2020 'Very Fast' CRISPR Enables Immediate, Synchronous Cleavage of Genomic Sites May 31, 2020 Germline Results From Tumor-Normal Sequencing Guides Precision Therapy in Advanced Cancer Patients May 31, 2020 Polygenic Risk Score, Family History Refine Breast Cancer Risk Assessment in CHEK2 Mutation Carriers Apr 30, 2020 Prostate Cells With Regenerative Capability Uncovered by Single-Cell Transcriptomics Apr 16, 2020 Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions Apr 15, 2020 Guardant360 Results in Alpelisib Trial Suggest Liquid Biopsy May Help Better Capture Non-Responders Premium Apr 15, 2020 Glioma Hypermutation May Not Correspond to Checkpoint Immunotherapy Response, Study Suggests Feb 27, 2020 Microbiome Composition Predicts Clinical Outcome Among Stem Cell Transplant Patients Feb 11, 2020 Healthcare Providers Try New Ways to Share Genetic Test Results With Patients, but Pitfalls Remain Premium Nov 27, 2019 MSK Study With Expanded Liquid Biopsy Panel Supports Value of Tumor-Normal Sequencing Premium Load More Breaking News In Brief This Week: Illumina, Personalis, Proteomedix, and More Ancient DNA Details Population Dynamics Within Andean Tiwanaku Civilization Genomic Data Spanning 2K Years Gives Glimpse of Etruscan Origins, Population Changes People in the News: New Appointments at Hologic, Akoya Biosciences, Caris Life Sciences, More At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change New Products Posted to GenomeWeb: Becton Dickinson, Cosmos-ID, OncoDNA, More The Scan US Booster Eligibility Decision The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions. Arizona Bill Before Judge The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction. Additional Genes Wales is rolling out new genetic testing service for cancer patients, according to BBC News. Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.