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The transcription-based subtypes could differentiate which SCLC patients respond to treatments, such as immune checkpoint inhibitors and PARP inhibitors.

In Nature this week: reference genomes for the platypus and echidna, single-cell RNA sequencing analysis of gastric adenocarcinoma, and more.

Researchers used single-cell RNA sequencing to delve into intra-tumoral heterogeneity in peritoneal carcinomatosis, identifying a potential prognostic signature.

Adaptive is rebranding its immunoSeq Dx assay as T-Detect and plans to submit for an EUA for a COVID-19 T-Cell response test by the end of the year.

In Genome Biology this week: mouse model for determining immunotherapy response, genomic changes that occur with non-small cell lung cancer metastasis, and more.

Researchers built a systematic map of protein-drug interactions to investigate the behaviors of cancer cells and the dependencies of treatment responses.

An MD Anderson-led team also used longitudinal single-cell sequencing to show how clonal architecture changed in response to AML treatment.

The DrBioRight system goes beyond NLP to produce "natural-language understanding" through AI as it creates automated dialog with researchers to speed up data analysis.

In PNAS this week: possible treatment targets in KRAS-mutated lung cancer, transcriptional analysis of mouse models lacking a p53 inhibitor, and more.

TargetCancer is activating two enrollment sites and setting up a remote consenting process so patients with rare cancers can be seen at local community hospitals.

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Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.

Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.

Science reports that a Dutch research funding agency is combating a ransomware attack.

In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.