McGill University

This Week in PLOS

In PLOS this week: tick salivary transcriptome, genetic risk scores for type 1 diabetes, and more.

Partnering with researchers at McGill University, the Johns Hopkins team that developed the method has now demonstrated its power in a much larger group of patients.

Genome Canada and its partners recently funded two new initiatives with C$255 that will back precision medicine, genomics, and technology development.

Stat News reports that researchers are not good at predicting whether a clinical trial will be successful.

In a study of nearly 45,000 people, researchers found that two variants in LPA each increase aortic stenosis risk by about a third, and about twofold in combination.

A study of gene expression data from 173 breast cancer patients identified subtype-specific associations between molecular processes in tumor and blood cells. 

Bit Too Confident

PLOS Biology study finds that cancer researchers tend to overestimate the extent to which preclinical studies may be reproducible.

In Nucleic Acids Research this week: MicrobiomeAnalyst, Cancer PanorOmics, and more

One speaker cited the success of screening Ashkenazi Jewish women for BRCA mutations, but another said extending testing to a wider population could be harder.

Researchers have released new tools for analyzing epigenomic data as part of the International Human Epigenome Consortium.

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Mice in New York harbor both antibiotic-resistant bacteria and novel viruses, according to a new analysis of their fecal microbiomes.

Human Heredity and Health in Africa Initiative has issued guidelines for genomic research in the region, according to Nature News.

The Associated Press reports that an ethicist predicts that prenatal diagnosis and other advances will lead to more choices being available to prospective parents.

In Genome Biology this week: approach to analyze alternative polyadenylation, algorithm to predict transcriptomic structural variations, and more.