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Max Planck

In PLOS this week: genetic adaptation in chimpanzees, transcriptional features of renal cell carcinoma, and more.

In Nature this week: native RNA sequencing and analysis of a human poly(A) transcriptome, nanopore sequencing-based method to analyze short tandem repeat expansions, and more.

Mitochondrial sequences suggest some haplogroups found in Finland today arrived in the region pre-Iron Age, though population distributions have shifted.

Using ancient DNA profiling, isotope analyses, and archeological clues, investigators saw high-status, male-centered families, along with more modest graves for unrelated individuals.

During the Black Death, Yersinia pestis isolates had low genetic diversity, but they diversified in multiple clades as the pandemic raged on.

In Science this week: four reviews examine what's known about the associations between genotype and phenotype, and more.

Using 350 human genomes from different populations, the two centers plan to develop a multi-genome reference sequence that is as complete as possible.

In PNAS this week: spatial transcriptomic approach for quantifying RNA transcripts within subcellular compartments, proteomic study of dental samples from individuals who lived during Ireland's Great Famine, and more.

For a Breakthrough

Winners of this year's Breakthrough Prize in the life sciences include researchers who studied neurodegenerative disorders and protein folding.

The Scientist reports on efforts to tease out what Neanderthal-derived alleles in modern humans do.

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A Harvard University professor has been charged with making false claims regarding funds he received from China, the New York Times reports.

Discover magazine reports that animal dissections might dissuade students from science careers, but that a firm has developed synthetic frogs for dissections.

Nature News reports that a US panel is reviewing current guidelines for federally funded gain-of-function viral research.

In PNAS this week: de novo mutation patterns among the Amish, an alternative RNA-seq method, and more.