The Broad Institute-led team has published its procedures, preliminary findings, and possible future applications for the consortium's open access database.
By comparing pre-treatment and post-relapse samples from vemurafenib-treated melanoma patients, researchers uncovered resistance-related cohesin complex mutations.
The Massachusetts-based clinical gene editing firm has obtained exclusive rights to use the engineered Cas9 variants developed by one of its co-founders.
With genotypes for hundreds of thousands of individuals, investigators uncovered 15 loci linked to major depressive disorder in individuals with European ancestry.
Researchers working on the Human Functional Genomics Project have begun to unravel genetic relationships and variations in human immune response.
The updated repository includes 265 drugs, 1,074 cell lines, as well as associated whole-exome sequencing and gene expression data among other datasets.
A high risk score was associated with worse memory, smaller hippocampi, and cognitive decline, and could be used to detect disease prior to the onset of symptoms.
The Food Allergy Science Initiative seeks to supply the basic scientific research needed to spur future development of diagnostics and therapeutics.
The analysis also indicates that vascular and smooth muscle tissues contribute to migraine pathophysiology.
Researchers identified a mutational signature that's more common in urothelial tumors with non-silent somatic mutations in the nucleotide excision repair gene ERCC2.
Russian CRISPR researcher moves along with plans to ultimately alter the genes of embryos of deaf couples, though awaits regulatory approval, Nature News reports.
University of California, San Francisco, researchers have uncovered a gene mutations that appears to make a father-son duo more efficient sleepers.
NPR reports a large health insurer has begun to cover some pharmacogenetic tests for psychiatric drugs.
In PLOS this week: genome-wide association study of non-syndromic orofacial cleft subtypes, epigenetic and transcriptomic analysis of pancreatic ductal adenocarcinoma, and more.