Close Menu

Mass General

Broad's CRSP pipeline repurposes and validates familiar tools and best practices from its research arm and also incorporates some new ones.

Data for tens of thousands of individuals pointed to SNPs mediating the decline in colorectal cancer risk in individuals who regularly take aspirin or related drugs.

The methods could help lead to a tool to predict off-target activity and design highly specific guide RNAs for use in clinical applications of CRISPR/Cas9.

The collaborators will explore how InterSystems' HealthShare health informatics platform can support genomic and clinical data integration and analysis

With exome sequencing data on nearly 10,000 individuals with or without early-onset myocardial infarction, researchers narrowed in on two genes prone to rare mutations in those at enhanced heart attack risk.

NEW YORK (GenomeWeb) – Naturally occurring mutations that disrupt NPC1L1 protein function are associated with lower plasma low-density lipoprotein levels and a reduced risk of coronary heart disease, investigators from the Myocardial Infarction Genetics Consortium

NEW YORK (GenomeWeb) – Researchers from the Broad Institute, Massachusetts General Hospital, Yale School of Medicine, and elsewhere have used a combination of genetic, gene expression, and epigenetic marker information to map the causal variants contributing to 21 inflammatory autoimmune conditio

NEW YORK (GenomeWeb) – EKF Diagnostics Holdings today said it and Massachusetts General Hospital have entered into a two-year research collaboration to develop EFK's PointMan assays for certain cancers.

NEW YORK (GenomeWeb) – Researchers reported in Science today that they were able to culture circulating tumor cells for genomic analysis and drug susceptibility testing.

NEW YORK (GenomeWeb) — Cells that make up brain tumors are more heterogeneous than previously thought, according to a new single-cell transcriptomic analysis appearing in Science today.

Pages

The University of California, Berkeley's Jennifer Doudna reflects at Science on the anniversary of the announcement of the birth of twin girls who underwent genome editing.

By studying its enamel proteome, researchers have found the ancient ape Gigantopithecus blacki belongs to a sister clade to that of orangutans.

Bloomberg Businessweek discusses genomics with BGI's Wang Jian.

In Science this week: researchers find transplanting the gut microbiome in mice affects physiology, and more.