Mass General
SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes
Using sequence data for tens of thousands of psychotic disease cases and controls, researchers have begun unearthing specific phenotypes linked to rare variants.
BostonGene Helping MassGeneral Improve Understanding of Follicular Lymphoma Progression, Treatment
The company will analyze tumor genetics and microenvironments to advance research into why some follicular lymphomas become aggressive and treatment response.
Protective, Risk-Linked APOE Alleles Affect Glial Cell Transcriptome
The APOEε4 allele is linked to the upregulation of a phagocytosis and proinflammatory gene set both in normal aging and Alzheimer's disease brains.
Lung Cancer Treatment Response Linked to Cancer-Associated Fibroblast Cell Subtypes
Starting from NSCLC tumor samples, researchers identified three cancer-associated fibroblast subtypes with distinct molecular and treatment response features.
Lung Cancer Features, Treatment Clues Emerge From 'Omic Analysis of Difficult-to-Treat Subtype
With genomic, proteomic, transcriptomic, and other molecular data, investigators defined subtypes of lung squamous cell carcinoma and potential treatment targets or biomarkers.