Mass General SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes Using sequence data for tens of thousands of psychotic disease cases and controls, researchers have begun unearthing specific phenotypes linked to rare variants. BostonGene Helping MassGeneral Improve Understanding of Follicular Lymphoma Progression, Treatment The company will analyze tumor genetics and microenvironments to advance research into why some follicular lymphomas become aggressive and treatment response. Protective, Risk-Linked APOE Alleles Affect Glial Cell Transcriptome The APOEε4 allele is linked to the upregulation of a phagocytosis and proinflammatory gene set both in normal aging and Alzheimer's disease brains. Lung Cancer Treatment Response Linked to Cancer-Associated Fibroblast Cell Subtypes Starting from NSCLC tumor samples, researchers identified three cancer-associated fibroblast subtypes with distinct molecular and treatment response features. Lung Cancer Features, Treatment Clues Emerge From 'Omic Analysis of Difficult-to-Treat Subtype With genomic, proteomic, transcriptomic, and other molecular data, investigators defined subtypes of lung squamous cell carcinoma and potential treatment targets or biomarkers. Jun 8, 2021 NIH Earmarks $38M for Consortium Studying Polygenic Risk Scores in Diverse Populations May 7, 2021 Guardant MRD Test Performs Well in Small Study as Tissue-Informed Debate Takes Shape Premium Apr 19, 2021 ACMG Presentation Highlights Broad Institute's Massive Expansion of COVID-19 Testing Program Apr 8, 2021 Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Apr 2, 2021 Alzheimer's Disease Genomes Lead to Novel Loci Involved in Synaptic Function Feb 9, 2021 European Project Sets Out to Harness Genomics Data, AI to Create New Predictive Tools Premium Feb 1, 2021 Interpace, Rutgers, Mass General Sign Deal for Pancreatic Cyst Risk Assessment Biomarker Oct 28, 2020 Finnish Population Genomics Study Uncovers Rare, Recessive Disease Candidates Premium Aug 27, 2020 Natera, MGH to Collaborate in Early-Stage Breast Cancer Clinical Trial of Targeted Therapy Aug 20, 2020 Polygenic Variation Affects Disease Risk From Monogenic Variants, Study Finds Jul 20, 2020 New CRISPR Base Editors Induce Targeted DNA Transversions Premium Jul 9, 2020 Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories Jun 30, 2020 Fluxergy, Mass General Brigham Partner to Evaluate Rapid COVID-19 Molecular Testing System Jun 11, 2020 Diversity Problem Hinders Adoption of Polygenic Risk Scores, According to ESHG Panel Jun 1, 2020 CRISPR Researchers Develop Dual-Deaminase Base Editing Platforms May 27, 2020 GnomAD Consortium Details Range of Human Genetic Variation From Large Dataset May 11, 2020 Day Zero Diagnostics Using CARB-X Award to Commercialize Antibiotic-Resistance Testing Platform Premium May 8, 2020 Dilated Cardiomyopathy Risk Loci, Polygenic Score Emerge From Heart Imaging GWAS May 6, 2020 Chan Zuckerberg Initiative Grants $750K to COVID-19 Studies Using Single-Cell Methods Apr 16, 2020 Biogen Launches Employee COVID-19 Biobank With Broad Institute, Partners HealthCare Load More Breaking News SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes People in the News: New Appointments at Myriad Genetics, Becton Dickinson, Delfi Diagnostics, More In Brief This Week: Virginia Commonwealth University, Dovetail Genomics, Lucid Diagnostics, and More New Products Posted to GenomeWeb: Bio-Rad, PerkinElmer, Ares Genetics, Purigen Biosystems, More Genetron Health, Fosun Ink Commercialization Deal for Seq-MRD Test in China MultiMuTHER Team Tracks Expression, Metabolite Relationships in Aging TwinsUK Participants The Scan More Boosters for US Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes. From a Pig A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports. For Privacy's Sake Wired reports that more US states are passing genetic privacy laws. Science Paper on How Poaching Drove Evolution in African Elephants In Science this week: poaching has led to the rapid evolution of tuskless African elephants.