Mass General
Gates Foundation Awards Multiple Dx, Omics Grants in August and September
Awardees include Imperial College London, the Africa Health Research Institute, Mylab, CHOP, and the Task Force for Global Health, among others.
Pancreatic Cancer Spatial Single-Cell Analysis Teases out Microenvironment Responses to Treatment
Researchers found features in the pancreatic ductal adenocarcinoma microenvironment that are related to chemotherapy resistance.
Rare Variant Disease Ties Found Using Large-Scale Sequencing Datasets
Researchers performed phenome-wide association analyses with exome or genome sequences for diverse UK Biobank, Mass General Brigham Biobank, and All of Us participants.
Raynaud's Syndrome Genetics, Biology Uncovered in GWAS, Functional Study
A large genome-wide association study and meta-analysis identified eight Raynaud's syndrome-related loci, pointing to multiple proposed disease mechanisms.
Labs, Doctors Still Grapple With Patient Recontact Despite Streamlined Variant Reclassification
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Although leading labs have coalesced around the value of protocols for making sure updated variant calls get to patients, strategies still vary and practical challenges remain.