Mass General

Researchers are now using the approach to allow genome-wide sequencing to monitor disease and to investigate treatment response and resistance without the need for tissue biopsy.

'Now the Hard Work'

Business Insider reports that researchers are making headway in linking genetic variants to mental illness risk.

Alterations affecting the antigen presentation-related gene B2M appeared to be over-represented in melanomas with checkpoint blockade non-response or resistance.

The initiative's four research projects will use use genetic and other technologies to detect and treat cancer at its earliest stages.

A new set of papers reveals a range of gene expression influencers, identified using thousands of samples collected for the Genotype-Tissue Expression project.

Verge is working with four academic institutions to create a broad resource for the translation of preclinical models of amyotrophic lateral sclerosis research.

The newly announced Microbiome Immunity Project seeks to discover links between autoimmune diseases and bacteria in and on the human body.

The collaborators have signed a two-year research and license option agreement to develop novel T-cell therapies for cancer using genome editing technology.

The partners aim to develop a diagnostic methodology for obtaining cancer cell molecular profiles to help guide immunotherapies.

Or Maybe OK

A new BioRxiv preprint says the variants another research team attributed to off-target effects of CRISPR/Cas9 could be natural variation, New Scientist reports.

Pages

Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.