Leiden University

A Dutch famine during World War II led to life-long epigenetic changes in individuals whose mothers were pregnant with them at the time.

Researchers found methylation mediators of obesity and other metabolic features by profiling individuals born after a famine called the Dutch Hunger Winter.

Backed by €15 million in EU funding, the Ubiquitous Pharmacogenomics Consortium seeks to implement preemptive testing at seven healthcare systems by 2020.

One group pointed out differences between study group characteristics, while the other wondered about the role of patient preference.

Through exome and targeted sequencing, researchers identified de novo mutations in at least two genes involved in a condition called Möbius syndrome.

Three individuals in a 17th century burial carried genetic signatures associated with Bantu- and non-Bantu speaking populations in parts of Cameroon, Nigeria, and Ghana.

The panel may prove useful in clinical trials of drugs interfering with mutant gene expression, the researchers said.

NEW YORK (GenomeWeb News) – Autoimmune molecular diagnostics firm Ignyta today said it is working with Leiden University Medical Center to evaluate epigenetic signatures of patients with early synovitis and rheumatoid arthritis.

FlexGen of the Netherlands said last week that China's BGI and Leiden University Medical Center will use its target enrichment technology to validate variants for the Genome of the Netherlands, or GoNL, project.

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Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.

Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.

Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.

In Science this week: gut microbiome influences liver cancer growth, spread; and more.