Logo

Leiden University

Polygenic Risk Scores Could Refine Breast Cancer Screening Recommendations
Premium

A recent study has found that a polygenic risk score of more than 300 variants could shift what screening recommendations for breast cancer women might receive.

Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response
Premium

Researchers have developed a computational method that considers uncommon CYP2D6 variants to assess patient-specific metabolism of tamoxifen and other drugs.

Ancient DNA Points to Multiple Early Migration Waves Into Caribbean

Ancient samples from more than a dozen archaeological sites suggests population movement from South America preceded by at least two earlier migration waves.

Human Glycome Project Forges Ahead With Support From New England Biolabs, Genos, Waters
Premium

The new partnership will support the analysis of glycans in 30,000 human samples by the end of 2021.

Biotech Support Group, Leiden University Medical Center Ink Cancer Biomarker Research Agreement

The group will define and quantify Stroma Liquid Biopsy biomarkers in Leiden University-collected sera to correlate them with Leiden's tumor-stroma ratio scoring methods.

Jan 31, 2018

Methylation Links Prenatal Famine to Obesity, Metabolic Features in Adulthood

Jan 24, 2017

Pharmacogenomics Consortium Aims to Make Testing Ubiquitous for European Patients
Premium

Dec 1, 2016

Study Suggesting Breast Cancer Patients at Low Genomic Risk Could Avoid Chemotherapy Criticized

Jun 12, 2015

Exome Sequencing Uncovers De Novo Mutations in Individuals With Rare Facial Paralysis Syndrome

Mar 10, 2015

Ancient DNA Reveals African Origins of Enslaved Individuals in Caribbean

Feb 5, 2015

Study Describes Blood Biomarkers of Huntington's Disease Progression
Premium

Nov 19, 2014

Transgenomic to Share Variant Information from Tuberous Sclerosis Complex Tests in Database

Feb 25, 2013

Ignyta, Leiden U Medical Center Evaluate Epigenetic Signatures for Synovitis, RA

Jan 31, 2012

BGI, Leiden to Use FlexGen Target Enrichment in Dutch Genome Project
Premium

Feb 3, 2011

Kreatech, LUMC Co-developing Tumor Tests

Nov 17, 2009

Helicos BioSciences Sells Sequencer to Dutch Medical Center
Premium

Mar 10, 2009

Roche NimbleGen, Neuromuscular Disorder Group to Merge CGH, Sequencing Data in Study
Premium

Mar 3, 2009

FlexGen Raises Financing to Commercialize Arrayer, Develop Applications
Premium

Breaking News
The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.