The researchers hope the datasets from their study can help to explain the effects of disease-associated variants on specific cell types of the immune system.
A La Jolla Institute for Allergy and Immunology-led team sequenced the transcriptomes of thousands of CD4+ T cells and compared their expression patterns.
The Human Immunome Program, which is part of the Human Vaccines Project, eventually plans to profile B-cell and T-cell receptors in more than 1,000 individuals.
By a GenomeWeb staff reporter
LIAI is preparing to assemble a permanent staff to run the screening facility, which is expected to include a manager and two full-time technicians, as well as a center director.
If MedImmune can develop and market a drug based on the discovery, it could be a financial boost to the institute, which hopes to diversify its revenue sources once cash from sole corporate sponsor Kirin Pharma USA dries up in 2010.
Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.
John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.
Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.
In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.