DNA sequence data from hundreds of individuals suggest that age, smoking, and alcohol use coincide with the expansion of clones containing NOTCH1 and PPM1D mutations.
The University of Texas MD Anderson Cancer Center's James Allison and Kyoto University's Tasuku Honjo have won this year's Nobel Prize in Physiology or Medicine.
In PNAS this week: AMD risk allele is protective against choroidal thickening, p53 transcriptional program is altered in cancer-associated fibroblasts, and more.
Kyoto University investigator has been fired for research misconduct, while Nobel Laureate Shinya Yamanaka has been penalized for lack of oversight, Retraction Watch reports.
Independent research teams took a look at the mutations, gene fusions, and other alterations that may inform pediatric T-ALL treatment and outcome predictions.
