Knowledge Foundation

Bay Area molecular diagnostics shop Wave 80 Biosciences is gearing up to evaluate its first product — a semi-quantitative HIV viral load assay that runs on the company's cartridge-based, near-patient, sample-to-answer testing system — in full-scale clinical trials by the end of t

The platform will combine immiscible phase filtration sample prep with automated amplification and detection, and is expected to have initial applications in point-of-care HIV testing in remote and resource-poor areas of the world. The company also sees the platform being used for decentralized molecular testing in more developed countries.

At last week's Sample Prep 2010 meeting in Baltimore, Md., microfluidics, integration, and automation were oft-cited as future market drivers in the area of sample prep for virus, toxin, and pathogen detection.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.