Karolinska Institute Whole-Genome Sequencing Aids Rare Disease Diagnosis in Stockholm-Area Healthcare System In the first five years of the Genomic Medicine Center Karolinska-Rare Disease program, molecular diagnoses were generated for about 40 percent of patients. Neanderthal-Origin Haplotype Provides Protection Against Severe COVID-19 The same researchers previously found a different Neanderthal-origin haplotype increased COVID-19 risk, highlighting their complex influence on humans. DNTR-Seq Latest Method to Combine WGS, Transcriptomics in Single Cells Premium The new plate-based protocol developed at the Karolinska Institute combines low-coverage WGS and SMART-Seq2 transcriptomics for single-cells. Years of Regular Endurance Exercise Leads to Transcriptomic Shifts in Muscles, Study Finds Sex differences in muscle gene expression were further reduced with long-term endurance exercise, an international research team found. Illumina, Genomic Medicine Sweden to Evaluate Sequencing-Based Leukemia Diagnostics The study will compare whole-genome sequencing and RNA sequencing to conventional diagnostic methods in about 450 acute leukemia patients in Sweden. Apr 27, 2020 Parkinson's Disease Cellular Genetic Analysis Uncovers Unexpected Role for Oligodendrocytes Apr 21, 2020 Curetis, Karolinska Institute Collaborate to Identify Bacterial Co-Infections in COVID-19 Patients Mar 19, 2020 Cartana Sees Human Cell Atlas Projects as Gateway to New Offerings, Market Adoption Premium Dec 19, 2019 Blood Cell Transcriptome Atlas Enables Study of Immune Disorders Dec 18, 2019 Nordic Project Aims to Investigate Link Between Mental Disorders and Cardiovascular Disease Premium Dec 3, 2019 SciLifeLab Researchers Develop Multiplexed Library Prep Method for FFPE Samples Premium Oct 2, 2019 Swedish Incubator Colibri to Support Molecular Diagnostics, Genomics Tools, Drug Discovery Startups Premium Sep 12, 2019 SciLifeLab, Broad Institute Researchers Go High Definition With Spatial Transcriptomics Premium Jul 15, 2019 Anorexia GWAS Yields Risk Loci with Metabolic, Psychiatric Overlap Jun 20, 2019 MGI Tech, Karolinska Institutet Form Microbiomics Research Alliance May 9, 2019 Circulating Tumor DNA Forecasts Recurrence in Non-Metastatic Colorectal Cancer May 2, 2019 Liquid Biopsy-Based Androgen Receptor Alterations Associated With Advanced Prostate Cancer Outcomes Apr 8, 2019 Proteome Analysis of Five Breast Tumor Subtypes Points to Additional Classifications Apr 2, 2019 Nordic Countries Invest $19M in Personalized Medicine Research Projects Premium Jan 2, 2019 Cancer Driver Gene Mutations Rise with Age in Otherwise Normal Esophageal Tissue Dec 5, 2018 Chan Zuckerberg Initiative Awards $52M in Grants for Neurodegenerative Disease Research Nov 21, 2018 Liquid Biopsy Shows Promise in Prostate Cancer Across Multiple Biomarkers Oct 16, 2018 Wound Healing Dynamics Traced With Single-Cell Transcriptomics Jun 20, 2018 Exome Sequencing Helps Diagnose Primary Antibody Deficiency Patients Apr 19, 2018 Single-Cell Study Details Development of Chemoresistant Breast Cancer Load More Breaking News Cytosine Base Editor Enables Genome-Wide Genetic Function Screening G42 Healthcare, Seegene to Offer Mobile Molecular Diagnostic Labs in Middle East, North Africa JP Morgan, Cowen Initiate Coverage of Singular Genomics Systems Top Five Articles on GenomeWeb Last Week: Danaher, Becton Dickinson, 23andMe, and More Berry Oncology, Alibaba Health Partner to Offer Early Cancer Screening, Health Services Roche Receives FDA EUA for PCR-Based, Point-of-Care SARS-CoV-2 Test The Scan Renewed Gain-of-Function Worries The New York Times writes that the pandemic is renewing concerns about gain-of-function research. Who's Getting the Patents? A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports. Other Uses CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2. PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.