Karolinska Institute
Hearing Loss GWAS Meta-Analysis Highlights Cochlear Structure Role in Hearing Impairment
Investigators saw a role for the stria vascularis in hearing loss with genetic data for 147,997 hearing loss cases and 575,269 controls, coupled with follow-up functional analyses in mice.
Diffuse Large B Cell Lymphoma Tumor, Microenvironment Features Explored With Single-Cell Atlas
Using single-cell RNA sequencing on more than 94,300 cells from 17 tumors, researchers identified expression clusters, tumor-microenvironment interactions, and more.
HIV Risk Reduced in Carriers of Allele Linked to Severe COVID-19
HIV infection risk was roughly 27 percent lower in individuals with a COVID-19 risk allele that reduced CCR5 chemokine receptor gene expression.
Rebus Biosystems Acquires IP, Assay Assets of EEL Transcriptomics
The EEL assay will be available for use on the Rebus Esper system through early access in the first half of 2022, followed by a commercial launch in June.
Whole-Genome Sequencing Aids Rare Disease Diagnosis in Stockholm-Area Healthcare System
In the first five years of the Genomic Medicine Center Karolinska-Rare Disease program, molecular diagnoses were generated for about 40 percent of patients.