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Johns Hopkins

John Littlefield Dies

John Littlefield, a pediatrician and geneticist, has died, the Baltimore Sun reports.

Johns Hopkins University researchers have developed a method called targeted error correction sequencing, or TEC-Seq, to increase liquid biopsy sensitivity.

Such analyses can help researchers pinpoint how various cancers evolve and determine the best kinds of tests to use to find certain disease information.

Speakers at the conference's opening plenary showed how their work in cancer research fit into the broad theme of 'Discover, Predict, Prevent, Treat.'

Qiagen will commercialize its research-use-only AdnaTest to detect AR-V7 from liquid biopsies to investigate resistance to drugs for advanced prostate cancer.

The technology, called Tunr, involves targeting translation elongation by introducing consecutive adenosine nucleotides into a gene coding sequence of interest.

The researchers also reported that the percentage of mutations attributable to replication errors, environmental exposures, and heredity varied by organ.

With new research and commercial test launches, clincians anticipate exciting new tools but judging quality and utility has become challenging.

The legal battle began last fall when LabCorp subsidiary Esoterix and Johns Hopkins University sued Myriad alleging infringement of four patents. 

International research teams collaborated to create five fully functioning synthetic yeast chromosomes, taking them one step closer to a whole synthetic genome.

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CBS This Morning highlights recent Medicare fraud involving offers of genetic testing.

Researchers find that many cancer drugs in development don't work quite how their developers thought they did, as Discover's D-brief blog reports.

Mariya Gabriel, a Bulgarian politician, is to be the next European Union research commissioner, according to Science.

In Science this week: a survey indicates that US adults are more likely to support the agricultural use of gene drives if they target non-native species and if they are limited, and more.