Preliminary results from the NASA Twins Study indicate changes in DNA methylation and gene expression due to life in space, Nature News says.
A subset of mutation-associated neoantigens appeared to be lost from lung or head and neck tumors that became resistant to anti-PD1 or anti-PD1 and anti-CLTA4 therapy.
A Johns Hopkins University team developed a framework to evaluate approaches to predicting cancer driver genes.
In PNAS this week: transcriptional control enables malaria parasite to get around disease control efforts, DNA methylation patterns in the Norway spruce, and more.
The technology, which is patent pending, can be used to help identify cancer patients who would respond to immune checkpoint inhibition treatment.
In Nature this week: modern European bison analysis, phased diploid genome assembly algorithms, and more.
Researchers from Pacific Biosciences and elsewhere tested their approach on Arabidopsis thaliana before applying it to wine grape and coral fungus genomes.
The model could shift which patients receive gene expression profiling assays but might not change the number of tests ordered.
Using data from the Simons Simplex Collection, researchers estimated that 5 percent of autism spectrum disorder cases may involve mosaic de novo mutations.
The Albert and Mary Lasker Foundation has announced this year's recipients of its prizes honoring basic and clinical research.
23andMe has a holiday popup shop at a mall and could open additional stores, Bloomberg reports.
By studying koalas and a retrovirus that infects them, researchers may have uncovered a new sort of 'immune response' that occurs at the genomic level, Agence France Presse reports.
NPR reports that the first person in the US given a gene editing-based therapy for a genetic disorder is heading home.
In Science this week: ancient genomes reveal social inequality within individual households, new method for quantifying genetic variation in gene dosage, and more.