Johns Hopkins

Sep 10, 2020

GTEx Studies Provide Comprehensive Map of Genetic Regulatory Variation Across Cell Types, Tissues

The GTEx Consortium, which has been working for 10 years, analyzed how genetic variants affect gene regulation, and how this contributes to disease and traits.

Aug 18, 2020

At Least Five Times

The Washington Post reports there were multiple introductions of SARS-CoV-2 into the capital region by the end of March 2020.

Aug 05, 2020

All-Cause Mortality Associated With New Sex-Specific Polygenic Risk Scores

A composite polygenic risk score helped cluster individuals by lifespan, though it appeared to be most informative for younger individuals.

Jul 09, 2020

Aneuploidy Common in Early-Stage Human Embryos, Single-Cell RNA-Seq Study Reveals

Analyzing transcriptome data from more than 1,000 cells from 74 embryos, a Johns Hopkins University-led team found aneuploid cells in 80 percent of embryos.

Jun 26, 2020

Slow Change

NPR reports that the SARS-CoV-2 genome does not appear to accumulate mutations quickly, which should help vaccine efforts.

Jun 17, 2020

Tomato Structural Variations Linked to Gene Expression, Traits

Researchers used long-read nanopore sequencing in 100 tomato varieties to uncover more than 230,000 structural variants in the tomato genome.

Jun 12, 2020

Science Papers Track SARS-CoV-2 in Northern California, Describe 'Very Fast CRISPR' Approach

In Science this week: multiple SARS-CoV-2 introductions into Northern California and the development of the 'very fast CRISPR' method.

Jun 11, 2020

'Very Fast' CRISPR Enables Immediate, Synchronous Cleavage of Genomic Sites

The technique could be used to study DNA repair at high resolution in space, time, and genomic coordinates, the researchers said.

Jun 09, 2020

PNAS Papers on Childhood Periodic Fever, Mutant TERT-BRAF Interactions, AML Microenvironment

In PNAS this week: genetic variants linked to a pediatric periodic fever syndrome, TERT promoter mutations influencing BRAF and MEK inhibitor response, and more.

May 18, 2020

Breast Cancer Susceptibility GWAS Highlights Dozens New Loci, Some Subtype-Specific

A genome-wide association study on hundreds of thousands of women with or without breast cancer implicated 32 new risk loci, including sites associated with specific subtypes.

Menu

Johns Hopkins

GTEx Studies Provide Comprehensive Map of Genetic Regulatory Variation Across Cell Types, Tissues

At Least Five Times

All-Cause Mortality Associated With New Sex-Specific Polygenic Risk Scores

Aneuploidy Common in Early-Stage Human Embryos, Single-Cell RNA-Seq Study Reveals

Slow Change

Tomato Structural Variations Linked to Gene Expression, Traits

Science Papers Track SARS-CoV-2 in Northern California, Describe 'Very Fast CRISPR' Approach

'Very Fast' CRISPR Enables Immediate, Synchronous Cleavage of Genomic Sites

PNAS Papers on Childhood Periodic Fever, Mutant TERT-BRAF Interactions, AML Microenvironment

Breast Cancer Susceptibility GWAS Highlights Dozens New Loci, Some Subtype-Specific

Pages

Breaking News

M2Gen Expands Partnership With Discovery Life Sciences

Mutations in Type I Interferon Immunity Genes Underlie Severe COVID-19

Palmetto Expands Coverage for Decipher Biosciences Prostate Cancer Test

Cepheid Multiplex SARS-CoV-2, Flu, RSV Test Nabs FDA Emergency Use Authorization

ASU Team Wins $6M in Government Funding to Develop Rapid Saliva Testing System for Coronavirus

In Brief This Week: Fluidigm, Thermo Fisher Scientific, Veracyte, and More

The Scan

This Time, Novavax

Shortened Visas for Some Students

New York's Own Review

Science Papers Examine Y Chromosomes of Archaic Humans, Schistosomiasis Therapeutic Targets