The study used a variety of sequencing and mapping technologies, including from Illumina, Pacific Biosciences, 10X Genomics, Bionano Genomics, and Oxford Nanopore.
With single-cell RNA-seq on thousands of cells from the lateral hypothalamic area of male and female mice, researchers saw dozens of glutamatergic and GABAergic neuron types.
Researchers have developed a new Alzheimer's disease mouse model with greater genetic diversity.
The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.
Researchers used CRISPR to engineer mice that have multiple genetic variants associated with late-onset AD to facilitate research into biomarkers and treatments.
The Jackson Laboratory scientists are aiming to create a molecular toolkit that allows for the precise and reversible manipulation of epigenetic modifications.
Jackson Laboratory is re-creating the genome of the female mouse from which its line of C57BL/6J mice descends, according to Nature News.
Participants in the pilot will begin developing the capabilities required for the planned data commons, including making data transparent and interoperable.
The Jackson Laboratory and Seven Bridges have won a $2 million grant to create a platform for coordinating research with patient-derived tumor xenograft data sets.
The Jackson Laboratory has filed a complaint accusing Nanjing University of breeding and re-selling its mouse models, the Hartford Courant reports.
The US Department of Justice has proposed a rule change to enable DNA to be collected from migrants, the Associated Press reports.
Bernard Fisher, a surgeon who changed how breast cancer is treated, has died at 101, the New York Times reports.
A Washington Post columnist writes that she is skeptical about DNA-based diets.
In PNAS this week: recurrent inactivation of DEPDC5 in gastrointestinal stromal tumors, taxonomic reliability of GenBank sequences, and more.