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Jackson Lab

With single-cell RNA-seq on thousands of cells from the lateral hypothalamic area of male and female mice, researchers saw dozens of glutamatergic and GABAergic neuron types.

New Mice for the Job

Researchers have developed a new Alzheimer's disease mouse model with greater genetic diversity.

The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.

Researchers used CRISPR to engineer mice that have multiple genetic variants associated with late-onset AD to facilitate research into biomarkers and treatments.

The Jackson Laboratory scientists are aiming to create a molecular toolkit that allows for the precise and reversible manipulation of epigenetic modifications.

Jackson Laboratory is re-creating the genome of the female mouse from which its line of C57BL/6J mice descends, according to Nature News.

Participants in the pilot will begin developing the capabilities required for the planned data commons, including making data transparent and interoperable.

The Jackson Laboratory and Seven Bridges have won a $2 million grant to create a platform for coordinating research with patient-derived tumor xenograft data sets.

Mouse Fight

The Jackson Laboratory has filed a complaint accusing Nanjing University of breeding and re-selling its mouse models, the Hartford Courant reports.

The research team is developing a computational system for studying the relationship between RNA structure and function.

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Two researchers are calling for education for scientists on defending facts.

Researchers were among those who marched in London this weekend to call for another vote on Brexit.

Duke has agreed to pay $112.5 million to settle a lawsuit regarding its handling of data falsified by biologist Erin Potts-Kant. 

In PLOS this week: genetic factors influencing inorganic arsenic metabolism and toxicity, a germline variant in the cell adhesion molecule-coding gene DSCAM, and more.