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Mouse for That

The Economist reports on the development of mouse models to study COVID-19.

In PLOS this week: transcriptomics-based strategy to study Alzheimer's disease heterogeneity, insecticide resistance diversity and evolution, and more.

Fresh off a new investment round, the British firm seeks to help research labs and biopharma companies manage population-level genomics research.

The alliance comes a few months after Shriners Hospitals established a new genomics institute in Tampa, Florida in partnership with Genome Medical.

The researchers are aiming to provide new insights as to which cancer patients will respond best to immunotherapy based on their genetic backgrounds.

Researchers at the Jackson Laboratory have tested an early version of the GenapSys sequencer and found it to have a very low mismatch error rate.

Clinicians found interpreting negative results and variants of uncertain significance to be challenging, according to an analysis presented at the NSGC annual meeting.

Microsoft is applying its Project Hanover AI to Jackson Laboratory's Clinical Knowledgebase to help tumor boards find appropriate therapies based on tumor mutations.

The study used a variety of sequencing and mapping technologies, including from Illumina, Pacific Biosciences, 10X Genomics, Bionano Genomics, and Oxford Nanopore.

With single-cell RNA-seq on thousands of cells from the lateral hypothalamic area of male and female mice, researchers saw dozens of glutamatergic and GABAergic neuron types.

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The Washington Post reports that the CDC's SARS-CoV-2 test issues reflect earlier ones it had with Zika virus testing.

NPR writes that even with thousands of new COVID-19 papers, each should be evaluated based on its own quality.

Researchers traced a gene cluster linked to COVID-19 severity to Neanderthals, the New York Times reports.

In PNAS this week: soil bacteria-derived small molecules affect centrosomal protein, microfluidics approach for capturing circulating tumor cells, and more.