Jackson Lab

Researchers used CRISPR to engineer mice that have multiple genetic variants associated with late-onset AD to facilitate research into biomarkers and treatments.

The Jackson Laboratory scientists are aiming to create a molecular toolkit that allows for the precise and reversible manipulation of epigenetic modifications.

Jackson Laboratory is re-creating the genome of the female mouse from which its line of C57BL/6J mice descends, according to Nature News.

Participants in the pilot will begin developing the capabilities required for the planned data commons, including making data transparent and interoperable.

The Jackson Laboratory and Seven Bridges have won a $2 million grant to create a platform for coordinating research with patient-derived tumor xenograft data sets.

Mouse Fight

The Jackson Laboratory has filed a complaint accusing Nanjing University of breeding and re-selling its mouse models, the Hartford Courant reports.

The research team is developing a computational system for studying the relationship between RNA structure and function.

Effect of Sex

Researchers find a number of traits differ by sex and could affect mouse model studies, according to Reuters.

The Jackson Lab has partnered with the Wenzhou Municipal People's Government, Ouhai District People's Government, and Wenzhou Medical University.

The ASM speaker said that strains collected from two different hospital systems also exhibited overlap in their SNP and other content.

Pages

Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.