By sequencing Vibrio cholerae isolates from Africa and Latin America, investigators got a look at the lineages leading to outbreaks over several decades.
An Institut Pasteur-led team genotyped various Pakistani populations to reconstruct the genetic history of descendants of the Indian Ocean slave trade.
With hundreds of bacterial genome sequences, researchers characterized horizontal gene transfer hotspots contributing to genome evolution and diversification.
Investigators used gene expression and immunological profiling to detect distinct immune responses in dengue virus-infected children with or without symptoms.
Using data for thousands of African individuals, researchers retraced migrations by Bantu language groups and ties to other populations in Africa and beyond.
International research teams collaborated to create five fully functioning synthetic yeast chromosomes, taking them one step closer to a whole synthetic genome.
By analyzing hundreds of rabies virus genomes from isolates collected over 65 years, researchers characterized evolutionary features in two main RABV groups.
The next-generation sequencing-based test is designed to detect bacteria and viruses in blood samples from patients with suspected infections, especially immunocompromised patients.
In PLOS this week: links between gut microbiome and colorectal cancer mutations, targeted sequencing uncovers genetic susceptibilities to epilepsy in Koreans, and more.
