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INSERM

Ewing Sarcoma Risk Locus Analysis Sheds Light on Cancer's Formation

Analyzing a chromosome 6 risk locus by long-read sequencing, researchers saw a combination of germline and somatic alterations interacting in the development of Ewing sarcoma.

Stroke Risk Contributors, Treatment Targets Uncovered in Cross-Ancestry GWAS

Starting with a GWAS meta-analysis that included more than 110,000 stroke patients, researchers found new risk loci and developed polygenic scores for risk prediction.

Alzheimer's Disease GWAS Meta-Analysis Leads to New Susceptibility Loci, Risk Score

After identifying 75 Alzheimer's disease-associated loci, researchers explored related pathways and came up with a genetic risk score for the disease.

Male Infertility Exome Sequencing Leads to New Diagnostic, Treatment Insights

Investigators identified potential causal variants in 16 genes, including meiotic pathway gene changes that coincided with fertility treatment failure.

Cartana Sees Human Cell Atlas Projects as Gateway to New Offerings, Market Adoption
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The Solna, Sweden-based company is currently expanding from offering in situ sequencing services to selling kits.

Jan 22, 2020

B Cell Gene Expression Profiling May Enable Cancer Immunotherapy CDx Test
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Jan 15, 2020

Presence of B Cells in Tumors Associated With Favorable Immunotherapy Outcomes

Jun 10, 2019

Alzheimer's Disease Potential Risk Variants Identified in Study of APOE4 Carriers, Noncarriers

Feb 5, 2018

Chloride Ion Channel Mutations Implicated in Hormone Condition Leading to Hypertension

Jan 26, 2018

Targeted Sequencing Panel Costs Average €607, New Analysis Finds

Dec 6, 2017

Philips-Led European Oncology Project Integrating Molecular Testing, Liquid Biopsy, Medical Imaging
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Nov 27, 2017

Philips, Partners Win €6.3M Grant to Develop Personalized Cancer Treatment Approach

Nov 3, 2017

Liver Cancer Genomes Reveal Mutational Signatures Associated With Alcohol, Other Factors

Mar 16, 2017

Six New Sporadic Dilated Cardiomyopathy Risk Loci Detected

Dec 21, 2016

Prion Proteins Detected With High Sensitivity, Specificity in Blood Samples

Oct 5, 2016

Pancreatic Cancer Aggressiveness Potentially Linked to Microenvironment Protein Marker

Jun 1, 2016

BRCA Data Sharing Effort Announces More Than 6K Variants, Reclassification of Hundreds of VUS

Apr 18, 2016

Ranomics Touts Functional Genomics Studies as Solution to Genetic Testing Market's VUS Challenge
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Feb 24, 2016

Team Ties Tumor Microenvironment to Metastasis in Colorectal Cancer

Aug 19, 2015

Sequencing Study IDs Neonatal Infections Involving Mutated Group B Strep Strains

May 5, 2015

With BRCA Share, Quest Hopes to Provide Field With Variant Database to Support Clinical Decisions
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Apr 21, 2015

Quest, Inserm Launch BRCA Datasharing Initiative; LabCorp First to Join

Mar 30, 2015

Exome Sequencing of Hepatocellular Carcinomas Reveals Disease Signature, Potential Treatment Targets

Dec 11, 2014

Tataa Biocenter Inks Licensing Deal with INSERM for ValidPrime Technology

Dec 8, 2014

IntegraGen Nets Exclusive Rights to Liver Cancer Gene Signatures

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The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.