An exome-wide association study involving almost 2,800 individuals with dilated cardiomyopathy led to six new and two known susceptibility loci.
Two research teams reported detecting prions using different versions of the same assay, and one said it could detect the proteins before the onset of symptoms.
A proteomic analysis of pancreatic ductal adenocarcinoma tumor and stromal samples led to a stromal protein that appears to coincide with tumor aggressiveness.
The initiative, launched last year by Quest and the French National Institute of Health and Medical Research, has reclassified 375 variants of unknown significance so far.
Ranomics is building a business around providing functional data on variants of unknown significance, starting with BRCA1 mutations.
Using data from more than 800 colorectal cancer samples, researchers concluded that features in the microenvironment may protect against metastasis.
A French team sequenced and compared Streptococcus agalactiae isolates from 19 mothers and their infected infants.
The field needs a database that can help inform variant classifications reported to patients, but Quest finds most publicly available resources aren't robust enough for this purpose.
In joining forces to support BRCAShare, Quest and LabCorp are taking on Myriad Genetics, which maintains a proprietary database with more than 1 million test results.
An INSERM-led team has uncovered new hepatocellular carcinoma mutational signatures that reflect exposure to certain disease risk factors.
Researchers suggest that genetic variations could influence the side effects people experience when using synthetic cannabinoids, the International Business Times reports.
An analysis has examined the makeup of researchers on Twitter and what they share, Nature News reports.
At Stat News, Jim Kozubek argues that the Broad Institute is pushing the boundary of what a nonprofit is.
In PNAS this week: gut microbes may affect honeybee weight, phenotype and gene expression changes in DiGeorge syndrome, and more.