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This Week in Science

In Science this week: algorithm to examine circadian expression of genes, and more.

Independent research teams identified mutations in a chloride ion channel gene in some cases of aldosteronism, a condition that can cause severe hypertension.

A team of French researchers estimated the total cost of performing clinical next-generation sequencing tests and found that consumables drive the price.

The new European initiative promises to deliver multiple new tests and methods for improving the treatment of breast cancer and rectal cancer.

Philips and its partners aim to combine liquid biopsy with magnetic resonance imaging to enable personalized cancer treatment.

An analysis of new and available liver cancer genomes led to 10 mutational signatures and six structural rearrangement signatures in hepatocellular carcinoma.

An exome-wide association study involving almost 2,800 individuals with dilated cardiomyopathy led to six new and two known susceptibility loci.

Two research teams reported detecting prions using different versions of the same assay, and one said it could detect the proteins before the onset of symptoms.

A proteomic analysis of pancreatic ductal adenocarcinoma tumor and stromal samples led to a stromal protein that appears to coincide with tumor aggressiveness.

The initiative, launched last year by Quest and the French National Institute of Health and Medical Research, has reclassified 375 variants of unknown significance so far.

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.

In Science this week: reduction in bee phylogenetic diversity, and more.