INSERM Cartana Sees Human Cell Atlas Projects as Gateway to New Offerings, Market Adoption Premium The Solna, Sweden-based company is currently expanding from offering in situ sequencing services to selling kits. B Cell Gene Expression Profiling May Enable Cancer Immunotherapy CDx Test Premium Researchers have identified immune cell gene expression signatures that could one day be developed into tests to predict response to treatment. Presence of B Cells in Tumors Associated With Favorable Immunotherapy Outcomes Three new studies have found that the presence of B cells in tertiary lymphoid structures in tumors is associated with a favorable response to immunotherapy. Alzheimer's Disease Potential Risk Variants Identified in Study of APOE4 Carriers, Noncarriers Using exome data from Alzheimer's disease cases and controls with or without the APOE4 risk allele, investigators identified potential risk-stratifying variants. Chloride Ion Channel Mutations Implicated in Hormone Condition Leading to Hypertension Independent research teams identified mutations in a chloride ion channel gene in some cases of aldosteronism, a condition that can cause severe hypertension. Jan 26, 2018 Targeted Sequencing Panel Costs Average €607, New Analysis Finds Dec 6, 2017 Philips-Led European Oncology Project Integrating Molecular Testing, Liquid Biopsy, Medical Imaging Premium Nov 27, 2017 Philips, Partners Win €6.3M Grant to Develop Personalized Cancer Treatment Approach Nov 3, 2017 Liver Cancer Genomes Reveal Mutational Signatures Associated With Alcohol, Other Factors Mar 16, 2017 Six New Sporadic Dilated Cardiomyopathy Risk Loci Detected Dec 21, 2016 Prion Proteins Detected With High Sensitivity, Specificity in Blood Samples Oct 5, 2016 Pancreatic Cancer Aggressiveness Potentially Linked to Microenvironment Protein Marker Jun 1, 2016 BRCA Data Sharing Effort Announces More Than 6K Variants, Reclassification of Hundreds of VUS Apr 18, 2016 Ranomics Touts Functional Genomics Studies as Solution to Genetic Testing Market's VUS Challenge Premium Feb 24, 2016 Team Ties Tumor Microenvironment to Metastasis in Colorectal Cancer Aug 19, 2015 Sequencing Study IDs Neonatal Infections Involving Mutated Group B Strep Strains May 5, 2015 With BRCA Share, Quest Hopes to Provide Field With Variant Database to Support Clinical Decisions Premium Apr 21, 2015 Quest, Inserm Launch BRCA Datasharing Initiative; LabCorp First to Join Mar 30, 2015 Exome Sequencing of Hepatocellular Carcinomas Reveals Disease Signature, Potential Treatment Targets Dec 11, 2014 Tataa Biocenter Inks Licensing Deal with INSERM for ValidPrime Technology Dec 8, 2014 IntegraGen Nets Exclusive Rights to Liver Cancer Gene Signatures Mar 19, 2014 Immune Gene Study Uncovers Cytokine Alterations Associated with Colorectal Cancer Progression Oct 14, 2013 IntegraGen Acquires Exclusive License to Metastatic Colon Cancer Biomarker May 23, 2013 Study of Normally Silent Somatic Tissue Genes Leads to Potential Prognostic Signature in Lung Cancer Feb 20, 2013 European Cardio Markers Consortium Launches Load More Breaking News Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found People in the News: New Appointments at Helix, Pacific Biosciences, SomaLogic, More New Products Posted to GenomeWeb: Amoy Diagnostics, Akoya Biosciences, Congenica, Lucence In Brief This Week: BGI, Gencove, Cepheid, Biocartis, Biognosys, Co-Diagnostics, More Florida Lab Owner Pleads Guilty to $6.9M COVID-19 False Billing Scheme Pacific Biosciences Outlines Progress on Short-Read Sequencing at JPM, Partners With Canexia Health The Scan Close Panel Vote on Califf Nomination The New York Times reports there was a close committee vote to advance the nomination of Robert Califf to lead the US Food and Drug Administration to the full Senate. Task Force Reports on Scientific Integrity Nature News writes that that a new task force report recommends that the US establish a cross-agency scientific integrity council. Across the Hall Genetic testing, closed-circuit cameras, and more show how a traveler, without any contact, infected others at a New Zealand quarantine facility, CNN reports. Science Paper Examines Influence of Chromatin Modifications on Obsessive-Compulsive Disorder In Science this week: genes regulating chromatin modification may contribute to OCD risk.