Ewing Sarcoma Risk Locus Analysis Sheds Light on Cancer's Formation
Analyzing a chromosome 6 risk locus by long-read sequencing, researchers saw a combination of germline and somatic alterations interacting in the development of Ewing sarcoma.
Stroke Risk Contributors, Treatment Targets Uncovered in Cross-Ancestry GWAS
Starting with a GWAS meta-analysis that included more than 110,000 stroke patients, researchers found new risk loci and developed polygenic scores for risk prediction.
Alzheimer's Disease GWAS Meta-Analysis Leads to New Susceptibility Loci, Risk Score
After identifying 75 Alzheimer's disease-associated loci, researchers explored related pathways and came up with a genetic risk score for the disease.
Male Infertility Exome Sequencing Leads to New Diagnostic, Treatment Insights
Investigators identified potential causal variants in 16 genes, including meiotic pathway gene changes that coincided with fertility treatment failure.
The Solna, Sweden-based company is currently expanding from offering in situ sequencing services to selling kits.