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Imperial College London

A genome-wide association study involving roughly 2,200 Swiss individuals argues against a role for common variants with major effects in the development of neurotic personality traits.

Based on genetic data on more than 500 Plasmodium falciparum isolates from around the world, an international research group has concluded that the malaria parasite likely migrated with humans from Africa around 60,000 to 80,000 years ago

By sequencing the spontaneously hypertensive rat genome and comparing it to the rat reference genome, researchers are gaining insights into the differences between the lab strains that may eventually help explain human hypertension.

In the second phase, 10 of 17 labs were able to generate gel images that fell within a 95-percent confidence level in an inter-laboratory study. As a result, the methods developed in both phases of the campaign, called Fixing Proteomics, now serve as standards by which proteomics researchers using 2D gels can benchmark themselves.

The international consortium led by Imperial College will screen genes and conduct GWAS for asthma influences.

By profiling metabolites in urine using NMR spectroscopy prior to drug exposure, a research group from Imperial College London and Pfizer found hints that may explain different responses to the painkiller acetominophen.

A study by the UK's Advanced Institute of Management Research claims that many companies find it increasingly difficult to partner with universities, despite recent efforts by the government to promote such collaboration. Study co-author Ammon Salter discussed the findings with BTW this week.

People in the News

Mari Baker is leaving Navigenics, Andrew von Eschenbach has joined a consulting firm, Jay Flatley takes a seat on Helixis' board, and more.

Imperial College London and its spinout DNA Electronics have created a prototype for the so-called SNP Dr., which is being developed under a £1.2 million project that also includes Pfizer.

Bioinformatics

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The US Patent and Trademark Office is opening another interference proceeding in the CRISPR patent fight.

There's increasing genetic evidence that a number of ancient hominins may have contributed to the human gene pool, according to Discover's The Crux blog.

The Japan News writes that Japan needs to seize the opportunity to ensure that a wide number of people benefit from personalized cancer treatments.

In Cell this week: messenger RNA expression and translation, RNA localization atlas, and more.