ICR

Targets for Treatment

UK researchers have uncovered about 80 proteins that could be targeted to treat prostate cancer, the Times reports.

The researchers found that both coding and non-coding alterations drive the early development of multiple myeloma.

Researchers used a capture Hi-C strategy to identify candidate target genes and pathways at dozens of loci previously linked to breast cancer susceptibility.

A study reported this week that measuring changes in the numbers of specific circulating tumor DNA mutations can rapidly identify breast cancer patients who will have better outcomes.

A GWAS and meta-analysis linked Hodgkin lymphoma risk to variants in sequences related to B cell development, immune function, and autoimmune disease risk.

Many molecularly distinct subgroups emerged from a meta-analysis bringing together more than 1,000 high-grade glioma or diffuse intrinsic pontine glioma cases.

Results of a new study offer preliminary evidence that blood tests could select patients for treatment, and track response and resistance.

Treat, Check, Monitor

Liquid biopsy tests of circulating DNA could guide prostate cancer treatment, the Guardian reports.

Two new studies have delivered a multitude of new markers linked to testicular cancer, as well as a better understanding of the genetic architecture of the disease.

New data points to strong predictive ability for a ddPCR-based test of AR copy number, while other companies are pursuing tests that target expression of AR splice variants.

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In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.