ICR Guardant AACR Data Highlights Value of Clinical Test Database to Drive Drug Resistance Discoveries Researchers used the company's large clinical-genomic database to characterize HRD reversion mutations and explore their potential function in patient resistance to PARP inhibitors. Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories Three research teams profiled proteomic, genomic, and other features in lung adenocarcinomas in Asia and other parts of the world, including cases in never-smokers. RB1 Alterations in Advanced Prostate Cancer Associated With Poor Outcome Using exome or transcriptome data from more than 400 metastatic, castration-resistant prostate cancer cases, researchers identified survival-related alterations in the RB1 gene. UK Group Develops Cancer Liquid Biopsy Assay to Detect Low-Level Mutations Premium The group plans to use the assay for translational studies on metastasis and drug resistance initially and to develop a clinical version later on. Chromosome Interactions at Promoters Reveal Non-Coding Colorectal Cancer Mutations Researchers found relevant non-coding mutations in colorectal cancer cell lines by systematically profiling chromosome interactions at promoter fragments. Sep 13, 2018 GWAS Links Six New Loci to Multiple Myeloma Risk, Uncovers Potential Mechanisms Jul 2, 2018 Cooperation Among Pediatric Brain Cancer Tumor Cell Subpopulations Boosts Tumorigenic Ability Jun 11, 2018 Prostate Cancer Meta-Analysis Leads to New Risk Loci, Polygenic Risk Score Jun 6, 2018 Prostate Cancer Study Suggests Patients With DNA Repair Mutations May Benefit From Immunotherapy May 14, 2018 Children With Specific Brain Tumors Could Benefit From Added Bevacizumab Apr 30, 2018 Study Links BRCA1/2 Germline Mutations to Platinum Drug Response in TNBC Apr 9, 2018 Multiple Myeloma Study Links More Than Three Dozen Genes to Disease Mar 12, 2018 Breast Cancer Risk Gene Candidates Revealed by Chromosome Interaction Profiling Mar 7, 2018 Clinical Trial Results Support Liquid Biopsy Monitoring to Predict Responders to Palbociclib Premium Dec 1, 2017 Hodgkin Lymphoma GWAS, Meta-Analysis Leads to Immune-Related Loci Sep 28, 2017 Pediatric Glioma Splintered Into Distinct Subgroups by Molecular Meta-Analysis Jun 23, 2017 Liquid Biopsy May Guide PARP Inhibitor Therapy for Prostate Cancer Premium Jun 12, 2017 New Testicular Cancer Markers Revealed in Studies Jun 1, 2017 Landscape Still Unclear for Prostate Cancer Therapy Prediction Tests as New Approaches Emerge Premium Dec 20, 2016 Some Testicular Cancer Cases Involve Rare Ciliary Gene Mutations Jun 22, 2016 Rare Colorectal Cancer Risk Variants ID'd in Exome Sequencing Study Apr 7, 2016 Royal Marsden, ICR Launch Pilot to Sequence Pediatric Cancer Patients' Tumors Premium Jan 8, 2016 GWAS Yields Locus Linked to Multiple Myeloma Survival Oct 27, 2015 UK Study Uncovers Four New Testicular Germ Cell Tumor Risk Loci Oct 1, 2015 Meta-Analysis Links Five New Variants to Brain Cancer Risk Load More Breaking News Guardant Health Files Motions to Dismiss, Change Venue in Illumina Patent Lawsuit In Brief This Week: SQI Diagnostics, T2 Biosystems, Enhanc3D, QuidelOrtho, More Illumina, Precision Health Research Singapore Partner for 100K Genomes Population Study 23andMe Fiscal Q4 Revenues Increase 14 Percent Local Coverage Determinations Roundup: Castle Bio, SkylineDx Ancient Genome Sequence Provides Look at Ancestry for Individual Who Perished at Pompeii The Scan Billion-Dollar Diversity Initiative The Howard Hughes Medical Institute is now accepting applications for its new $1.5 billion initiative to boost the diversity of the scientific workforce. Biotech Co-Founder Arrested A co-founder of a Los Angeles-based biotech company has been arrested in connection with a murder-for-hire scheme, according to Endpoint News. Return of the Tasmanian Tiger The Washington Post reports that a team in Australia is working to bring the thylacine back from extinction. Nature Papers on Genome of Individual From Pompeii, CircRNA Study Best Practices, More In Nature this week: first sequenced genome of a person from Pompeii, best practice guidelines for circRNA studies, and more.