Exome sequencing data for hundreds of testicular germ cell tumor patients led to the discovery of rare mutations affecting cilia-microtubule genes.
Sequencing the exomes of more than 1,000 individuals with familial colorectal cancer revealed rare variants in several new candidate risk genes.
The researchers plan to enroll 400 patients in the pilot, with the goal of increasing the availability of targeted therapies to pediatric cancer patients.
Researchers identified a germline variant on chromosome 6 that corresponded to overall survival times in multiple myeloma patients from four study cohorts.
Combining the new risk variants with those found in the past, researchers came up with a risk score that may eventually help find those most susceptible to the disease.
An Institute of Cancer Research-led team conducted a meta-analysis that uncovered five new variants linked to glioma development, including one that greatly increases risk of glioblastoma.
A new study suggests ctDNA in post-treatment blood samples may help predict relapse in early stage breast cancer patients treated with chemotherapy and surgery.
As part of the Myeloma XI trial, a UK-led team used exome sequencing on 463 individuals with myeloma to look for mutations related to survival patterns.
Researchers tracked down two new risk variants in samples from around 100,000 breast cancer cases and controls.
Harold Varmus, a former NIH director, says that proposed reductions to the agency's budget are worrisome.
The Genome 10K project is to sequence about 10,000 vertebrate genomes, including ones of endangered species, Digital Trends reports.
The new Coalition to Save NIH Funding aims to educate lawmakers and the public on the significance of biomedical research.
In PLOS this week: analysis of viral sequences from human blood samples, gut microbiomes of heart failure patients, and more.