ICGC

Two new analyses have identified driver genes, altered pathways, mutational signatures, and other molecular features across two dozen cancer subtypes.

Members of the International Cancer Genome Consortium identified four main groups of HER2-positive breast tumors using genome sequencing and expression arrays.

TheSTARPlatform includes tools for analyzing genomic data from raw sequence through to variants calls as well as for compressing and storing data.

Researchers shared results from a benchmark study both identifying weaknesses and laying the groundwork for more accurate characterization of somatic mutations.

The group found that a combination of algorithms performs better than any one single algorithm.

Researchers did genome sequencing and copy number testing on samples from 100 pancreatic ductal carcinoma patients, building on prior ICGC exome findings.

NEW YORK (GenomeWeb) – A team from Japan and the US used a combination of whole-genome sequencing, exome sequencing, and "oncovirome" sequencing to scrutinize matched tumor and normal samples from more than 500 individuals from different populations who had a form of liver cancer called hepatocel

NEW YORK (GenomeWeb) – By unraveling the order in which mutations turn up in esophageal adenocarcinoma and the non-cancerous conditions that precede it, members of the International Cancer Genome Consortium have found recurrently mutated genes that may help in esophageal cancer prediction and ear

NEW YORK (GenomeWeb News) – The International Cancer Genome Consortium today announced it has made data from more than 10,000 cancer genomes available to the research community.

NEW YORK (GenomeWeb News) – A search for low-frequency cancer driver genes suggests truncating mutations to a transcription factor gene called CUX1 may be the impetus for cancer formation in a small but significant subset of cases across several cancer types.

Pages

Customers might want to consider what they might learn about their risk of diseases like Alzheimer's before snagging the genetic testing kits that are on many gift guides this year, NJ.com writes.

The Wall Street Journal reports there is uncertainty surrounding whether He Jiankui's embryo editing did what he said it did.

Stat News reports that the pause on procuring fetal tissue for intramural US National Institutes of Health research will soon affect additional labs there.

In Nature this week: genomic analysis of the invasive fall webworm, amp of constrained coding regions within the human genome, and more.