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ICGC

Two new analyses have identified driver genes, altered pathways, mutational signatures, and other molecular features across two dozen cancer subtypes.

Members of the International Cancer Genome Consortium identified four main groups of HER2-positive breast tumors using genome sequencing and expression arrays.

TheSTARPlatform includes tools for analyzing genomic data from raw sequence through to variants calls as well as for compressing and storing data.

Researchers shared results from a benchmark study both identifying weaknesses and laying the groundwork for more accurate characterization of somatic mutations.

The group found that a combination of algorithms performs better than any one single algorithm.

Researchers did genome sequencing and copy number testing on samples from 100 pancreatic ductal carcinoma patients, building on prior ICGC exome findings.

NEW YORK (GenomeWeb) – A team from Japan and the US used a combination of whole-genome sequencing, exome sequencing, and "oncovirome" sequencing to scrutinize matched tumor and normal samples from more than 500 individuals from different populations who had a form of liver cancer called hepatocel

NEW YORK (GenomeWeb) – By unraveling the order in which mutations turn up in esophageal adenocarcinoma and the non-cancerous conditions that precede it, members of the International Cancer Genome Consortium have found recurrently mutated genes that may help in esophageal cancer prediction and ear

NEW YORK (GenomeWeb News) – The International Cancer Genome Consortium today announced it has made data from more than 10,000 cancer genomes available to the research community.

NEW YORK (GenomeWeb News) – A search for low-frequency cancer driver genes suggests truncating mutations to a transcription factor gene called CUX1 may be the impetus for cancer formation in a small but significant subset of cases across several cancer types.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.