An analysis of post-mortem brain transcripts led to Alzheimer's-related alternative gene splicing and expression events, including those influenced by known risk alleles.
Researchers used brain expression data from mice with well-documented sleep traits to identify gene networks that overlap with those in human depression.
Using omics and other data, researchers performed network analyses that pointed to interactions between human herpesviruses and other Alzheimer's disease risk factors.
With RNA sequencing on blood samples taken before, during, and after peanut exposure, investigators searched for acute allergy-related genes and cell types.
A genome-wide association study meta-analysis that used average principal components to consider composite body shape traits led to six new genetic loci.
Researchers at the annual meeting of the American Association for Cancer Research discussed their efforts to use genomics to protect patients from radiotherapy toxicity.
By analyzing genomic data from nearly 590,000 apparently healthy individuals, researchers uncovered 13 carriers of serious Mendelian disease mutations.
In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.
