Icahn School of Medicine Alzheimer's Disease Subtypes Proposed From Gene Expression Profiles of Brain Regions Investigators identified five expression subtypes spanning three broader clusters in postmortem parahippocampal gyrus samples from Alzheimer's patients. IBD Polygenic Risk Scores Improved With Data From Multiple Ancestral Backgrounds The researchers also examined the contribution of rare variants to inflammatory bowel disease to find a potential targetable pathway. Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers An integrated proteogenomic analysis led to previously unappreciated treatment targets or prognostic markers in craniopharyngioma, high-grade glioma, and other tumor types. People in the News: New Appointments at Natera, Quanterix, Sophia Genetics, More Helio Heath Aims to Market Blood-Based Liver Cancer Screening Assay in Early 2021 Premium The firm is engaged in multiple clinical validation trials and aims to raise more than $100 million to launch its Helio Liver Test in the US early next year. Oct 16, 2020 SARS-CoV-2 Protein Interaction Study Reveals Key Proliferation Pathways, Possible Drug Targets Premium May 7, 2020 Fluidigm Q1 Revenues Fall 8 Percent Mar 16, 2020 Mount Sinai-Led Consortium, Fluidigm Developing Epigenetic Coronavirus Dx Jan 23, 2020 Autism Sequencing Study Uncovers New Disease-Associated Genes, Functional Clues Jun 13, 2019 Mount Sinai Gets $27.8M DARPA Grant for Epigenetic Tech to Measure WMD Exposure May 1, 2019 Bipolar Disorder Risk Loci Reported From Psychiatric Genomics Consortium GWAS Apr 30, 2019 PCOS Traits Tied to Rare Variants in Testosterone-Related Gene Mar 25, 2019 Schizophrenia Genes, Pathways in Brain Identified With Transcriptome Imputation Approach Dec 13, 2018 PsychENCODE Studies Explore Brain Development, Neuropsychiatric Regulatory Features Oct 18, 2018 Mount Sinai Researchers Develop Protein Barcoding Technology for Single-Cell CRISPR Screening Oct 8, 2018 Transcriptome Analyses Link Alzheimer's Disease With Brain Gene Splicing, Expression Aug 13, 2018 Mt. Sinai Researchers Use Multi-Omics Approach to Personalize Relapsed Multiple Myeloma Treatment Jul 25, 2018 Sleep, Depression Appear to Involve Shared Gene Networks Jun 21, 2018 Systems Biology Study of Alzheimer's Disease Supports Ties to Virus Dec 5, 2017 Acute Peanut Allergy Contributors Suggested by Blood Transcriptomic Study Sep 26, 2017 Autism Heritability Estimate Updated in New Analysis of 2014 Swedish Study Nov 23, 2016 Loci Linked to Body Shape Emerge From Composite Phenotype GWAS Meta-Analysis Apr 20, 2016 Burgeoning Radiogenomics Efforts Aim to Improve Cancer Therapy, Reduce Toxicities Premium Apr 11, 2016 Apparently Healthy Carriers of Mendelian Mutations Detected by Resilience Project Pilot Study Oct 12, 2015 ASHG Talk Describes Ability to Detect Detailed Ancestry Data for Biobank Participants Across NYC Load More Breaking News Children With Autism May Have Underdeveloped Gut Microbiomes, Metagenomic Analysis Finds Kiromic BioPharma Acquires InSilico Solutions Bio-Rad Laboratories, 10x Genomics Settle IP Lawsuits, Sign Global Cross-Licensing Agreement Scope Fluidics Obtains CE Mark for PCR-Based SARS-CoV-2 Panel MeMed COVID-19 Prognostic Test Receives CE Mark ERS Genomics Licenses CRISPR IP to Japan SLC The Scan Dropped Charges The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal. More Kids The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children. PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more. Purnell Choppin Dies Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.