Icahn School of Medicine

The platform integrates whole exome and RNA sequencing for downstream RNA-based drug repurposing to treat patients with relapsed multiple myeloma.

Researchers used brain expression data from mice with well-documented sleep traits to identify gene networks that overlap with those in human depression.

Using omics and other data, researchers performed  network analyses that pointed to interactions between human herpesviruses and other Alzheimer's disease risk factors.

With RNA sequencing on blood samples taken before, during, and after peanut exposure, investigators searched for acute allergy-related genes and cell types.

Researchers have increased their estimate of the heritability of ASD to 83 percent based on a reanalysis of their prior study of Swedish families.

A genome-wide association study meta-analysis that used average principal components to consider composite body shape traits led to six new genetic loci.

Researchers at the annual meeting of the American Association for Cancer Research discussed their efforts to use genomics to protect patients from radiotherapy toxicity.

By analyzing genomic data from nearly 590,000 apparently healthy individuals, researchers uncovered 13 carriers of serious Mendelian disease mutations.

Researchers are combining identity-by-descent-based ancestry information with electronic health records and self-reported ancestry information for thousands of New Yorkers. 

The designation includes an $8.5 million grant, which will be used to support research programs, facilitate researcher recruitment, and improve community engagement.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.