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Icahn School of Medicine

Alzheimer's Disease Subtypes Proposed From Gene Expression Profiles of Brain Regions

Investigators identified five expression subtypes spanning three broader clusters in postmortem parahippocampal gyrus samples from Alzheimer's patients.

IBD Polygenic Risk Scores Improved With Data From Multiple Ancestral Backgrounds

The researchers also examined the contribution of rare variants to inflammatory bowel disease to find a potential targetable pathway.

Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers

An integrated proteogenomic analysis led to previously unappreciated treatment targets or prognostic markers in craniopharyngioma, high-grade glioma, and other tumor types.

People in the News: New Appointments at Natera, Quanterix, Sophia Genetics, More

Helio Heath Aims to Market Blood-Based Liver Cancer Screening Assay in Early 2021
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The firm is engaged in multiple clinical validation trials and aims to raise more than $100 million to launch its Helio Liver Test in the US early next year.

Oct 16, 2020

SARS-CoV-2 Protein Interaction Study Reveals Key Proliferation Pathways, Possible Drug Targets
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May 7, 2020

Fluidigm Q1 Revenues Fall 8 Percent

Mar 16, 2020

Mount Sinai-Led Consortium, Fluidigm Developing Epigenetic Coronavirus Dx

Jan 23, 2020

Autism Sequencing Study Uncovers New Disease-Associated Genes, Functional Clues

Jun 13, 2019

Mount Sinai Gets $27.8M DARPA Grant for Epigenetic Tech to Measure WMD Exposure

May 1, 2019

Bipolar Disorder Risk Loci Reported From Psychiatric Genomics Consortium GWAS

Apr 30, 2019

PCOS Traits Tied to Rare Variants in Testosterone-Related Gene

Mar 25, 2019

Schizophrenia Genes, Pathways in Brain Identified With Transcriptome Imputation Approach

Dec 13, 2018

PsychENCODE Studies Explore Brain Development, Neuropsychiatric Regulatory Features

Oct 18, 2018

Mount Sinai Researchers Develop Protein Barcoding Technology for Single-Cell CRISPR Screening

Oct 8, 2018

Transcriptome Analyses Link Alzheimer's Disease With Brain Gene Splicing, Expression

Aug 13, 2018

Mt. Sinai Researchers Use Multi-Omics Approach to Personalize Relapsed Multiple Myeloma Treatment

Jul 25, 2018

Sleep, Depression Appear to Involve Shared Gene Networks

Jun 21, 2018

Systems Biology Study of Alzheimer's Disease Supports Ties to Virus

Dec 5, 2017

Acute Peanut Allergy Contributors Suggested by Blood Transcriptomic Study

Sep 26, 2017

Autism Heritability Estimate Updated in New Analysis of 2014 Swedish Study

Nov 23, 2016

Loci Linked to Body Shape Emerge From Composite Phenotype GWAS Meta-Analysis

Apr 20, 2016

Burgeoning Radiogenomics Efforts Aim to Improve Cancer Therapy, Reduce Toxicities
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Apr 11, 2016

Apparently Healthy Carriers of Mendelian Mutations Detected by Resilience Project Pilot Study

Oct 12, 2015

ASHG Talk Describes Ability to Detect Detailed Ancestry Data for Biobank Participants Across NYC

Breaking News
The Scan

Dropped Charges

The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal.

More Kids

The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children.

PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS

In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more.

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.