HUPO
Human Proteome Project Hits 90 Percent Coverage of Predicted Proteins
A decade after its launch, the effort has detected almost 18,000 human proteins and is shifting its focus more on different protein forms and functional data.
The 2010s saw major strides made through several large-scale initiatives aimed at mapping the human proteome and developing approaches for clinical work.
Gathering last week in Australia, the community continued its years-long push towards increased clinical relevance and integration with other omics disciplines.
The group's meeting this week evidenced the ongoing shift towards analyzing proteins in the context of specific isoforms, complexes, and cells.
The group has identified proteins from nearly 90 percent of the predicted protein-coding genes, though the remaining 10 percent present significant challenges.