Teams studying kidney and skin cancers independently implicated SWI/SNF chromatin remodeling mutations in checkpoint blockade immunotherapy response.
A Harvard-led team used genome editing to prevent inherited deafness in mice.
In Nature this week: genome-editing to treat hearing loss in mice, juvenile myelomonocytic leukemia subgroups, and more.
In PNAS this week: effect of human genetic variation on CRISPR-Cas9 gene editing, expression profiles of breast cancer, and more.
The researchers suggested that human genetic variation should be taken into consideration in the design and evaluation of CRISPR-based therapies.
In PLOS this week: HIV-1 genetic diversity in Bangalore; gene variants and noise-induced hearing loss; and more.
The Danish informatics firm is exploring analytical tools for its InWeb_InBioMap network, which currently contains more than 700,000 protein-protein interactions.
Google expects its newly released open-source update to DeepVariant to improve the accuracy of variant calling, particularly in plant and animal genomes.
In Nature this week: NetSig statistic for analyzing cancer genomes, and more.
Retraction Watch reports that Nobel Laureate Jack Szostak has retracted a 2016 Nature Chemistry paper.
According to New Scientist, GEDmatch changed its terms and conditions over the weekend to opt its users out of law enforcement searches.
The Atlantic looks into time spent pursuing gene leads generated through candidate gene studies.
A twin study uncovers evidence that genes may influence whether someone gets a dog, Martha Stewart reports.
In PNAS this week: Cdx2 cells can help regenerate heart tissue in mice following a heart attack, PIWI-interacting small RNA levels in human cancer, and more.