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Using SNP and expression microarrays, a team of researchers from Switzerland, the UK, and the US has uncovered cell type-specific differences in regulatory variant function within three different human cell types.

In a randomized, controlled trial of more than 150 adults, researchers involved in the REVEAL study found that learning APOE status did not seem to increase psychological risk for individuals with a parent affected by Alzheimer's disease.

Two studies appearing in the latest issue of the Journal of the American Medical Association examine the applicability of cardiovascular biomarkers for diagnostic and therapeutic development.

The researchers claim that their method, published in Nature Methods this week, is less expensive and more flexible than existing array- or solution-based targeted enrichment methods. They also demonstrate that it can be used both for calling SNPs and detecting copy number variations.

Azco will provide pre- and post-sales support, start-up reagents, applications support, on-site installation, user training, on-site warranty support, and ongoing technical support, which will increase the price of the platform.

Over the next year or so, Polonator developers plan additional improvements, including reagent kits, increased read lengths, and a simpler library preparation protocol. By 2010, they expect the output per run to increase tenfold, to 100 gigabases.

In work that it says verifies the authenticity of its study sequencing the T. rex, a team of researchers has identified proteins this time from an 80-million-year-old duck-billed hadrosaur.

For the second time, researchers have shown that dinosaur soft tissue and protein can survive for millions of years and yield informative peptide sequences.


A study of families explores how children transmit SARS-CoV-2, according to the Associated Press.

US Agricultural Research Service scientists have sequenced the genome of the Asian giant hornet.

According to the Economist, pooled testing for COVID-19 could help alleviate strains on testing labs.

In Science this week: MIT researchers outline approach dubbed translatable components regression to predict treatment response among IBD patients.