By sequencing and comparing the genomes of tuberculosis bacteria from latent, active, or reactivated macaque infections, researchers have found evidence that the bugs mutate during all three infection scenarios.
By looking for signals of natural selection in Plasmodium falciparum and performing a genome-wide association study of resistance, an international research team has identified genes suspected of contributing to resistance in the malaria parasite.
Whole-genome analyses are poised to transform pathology and other aspects of medicine, Mark Boguski told attendees at the American College of Medical Genetics meeting this weekend, but require improved resources for interpreting genetic variants.
Using global run-on sequencing and chromatin immunoprecipitation in Drosophila cells, a team of scientists from Massachusetts and New York has learned more about how males make the most of their single X chromosome.
A meta-analysis of several genome-wide, cell-based Drosophila RNAi screens, in conjunction with a focused RNAi screen, indicated that the rate of false negatives in such experiments is at least 8 percent.
As part of its investment in Alacris, Qiagen receives an exclusive option to license biomarkers identified through the company's genomics data-analysis platform and develop them into PCR-based assays for use in molecular diagnostic and theranostic applications or biomedical research.
Using digital gene expression analyses, Harvard Medical School and Helicos Biosciences researchers have shown that mouse and human cancers tend to over-express satellite repeats from parts of the genome that aren't typically transcribed in differentiated cells.
Researchers with the "model organism Encyclopedia of DNA Elements" Consortium today described some initial findings from their functional studies of the Drosophila melanogaster and Caenorhabditis elegans genomes.