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In PNAS this week: spatial transcriptomic approach for quantifying RNA transcripts within subcellular compartments, proteomic study of dental samples from individuals who lived during Ireland's Great Famine, and more.

By sequencing an Indus Valley Civilization representative and related individuals, investigators learned more about the South Asian ancestry, farming history, and languages.

In Genome Biology this week: analysis of colorectal cancer progression, secretion system used by Vibrio cholerae, and more.

The program, launched last year, is designed to help early-career investigators who have primarily worked within groups pursuing independent research.

The international firm is one of several pharmaceutical companies emphasizing new single-cell technologies to improve existing drugs and find new ones.

The NAM, NAS, and Royal Society have formed a commission to develop a framework on the proper use of genome editing, and convened its first meeting in Washington, DC, this week.

By analyzing metagenomic sequences found in thousands of human mouth and gut samples, researchers tracked down almost 45.7 million distinct microbial genes.

In PNAS this week: emerging songbird pathogen Mycoplasma gallisepticum, CRISPR-Cas9-based knockdown finds role for lipoprotein transport in viability, and more.

In Cell this week: malignant cellular states in glioblastoma, method for predicting long-term outcomes among cancer patients, and more.

Researchers developed a system for continuous evolution of base editors, which should continue to improve their functionality.

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A German shepherd called Nala has had her genome sequenced.

A coronavirus serology test garners Emergency Use Authorization from the US Food and Drug Administration, but the Los Angeles Times asks: how will tests like that be used?

Certain gene variants in conjunction with a healthy lifestyle may keep brains young, according to New Scientist.

In Science this week: increased CD8 T cell density and increased IFN-gamma response may indicate metastatic prostate cancer patients who will respond to immune checkpoint blockade therapy.