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In PNAS this week: core Pseudomonas aeruginosa genome, study of ancient Paget's disease of the bone, and more.

Investigators identified a set of inflammatory proteins that appears to coincide with current and future risk of end-stage renal disease in individuals with diabetes.

The TATTON study found a combination therapy could treat some EGFR-positive lung cancer patients who developed MET-based resistance, but the best way to gauge MET status isn't yet clear.

A team compared expression in duodenum samples from active celiac cases, cases in remission, and unaffected controls, identifying active disease-related expression shifts.

The group published results showing its method can faithfully recapitulate genome-wide measures of DNA repair deficiency using much smaller sequencing panels.

If cancer patients carrying the variants could be identified early, their therapeutic strategy could be altered to reduce their risk of cardiomyopathy.

In Science this week: NASA Twins Study examines biological effects of a year in space, and more.

In Nature this week: durum wheat genome assembly, approach for analyzing joint genetic architecture of complex traits, and more.

The Seattle-based firm's PickSeq platform integrates cell imaging and extraction tools for downstream RNA enrichment, sequencing, and targeted biomarker discovery.

Multi-drug resistant Enterococcus faecalis isolates from a Wisconsin hospital contained independent mutations falling at overlapping resistance-related loci.

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Researchers uncovered the HIV virus within a tissue sample collected in 1966, the Atlantic reports.

Nature News reports there are a handful of clinical trials underway to evaluate vaginal microbiome seeding of newborns born via caesarian section.

The Washington Post writes that humans may have contributed to the extinction of cave bears some 20,000 years ago.

In PLOS this week: gene variant may protect against trypanosomiasis, GLIS3 role in type 2 diabetes, and more.