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In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.

Investigators detected more than 100 risk loci for primary open-angle glaucoma, with mostly similar effects in people with European, Asian, or African ancestry.

A pair of studies published this week present an analysis of a real, large-scale testing pooling effort as well as analyses of how to further improve such strategies.

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.

In PNAS this week: single-cell whole-genome amplification approach for SNV detection, immune features linked to bone regeneration, and more.

A new genome-wide association study in Nature Communications uncovers five dozen loci linked to frequency of afternoon naps.

The Economist reports that a single genetic change could have enabled vertebrates to leave the water.

Both germline variants and somatic tumor variants linked to disease are more likely to disrupt protein-protein interactions than other variants.

As researchers embrace single-nucleus analysis to probe previously intractable tissues, companies are trying to deliver more reliable sample preparation.

Researchers have developed a higher-resolution in situ RNA sequencing method that relies on physically expanding a polymer network that holds the RNA.

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NPR reports that researchers have developed chimeric embryos as part of work toward growing human organs in animals for organ transplants.

According to the Washington Post, the Biden Administration is set to make changes to federal restrictions on fetal tissue research.

In Science this week: approach to isolated trace DNA from archaic humans from sediments, and more.

Texas Monthly looks into the DNA Zoo being collected by Baylor College of Medicine researchers.