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Mar 02, 2021

PNAS Papers on Myelopathy GWAS in Japan, Hypertrophic Cardiomyopathy, MRSA Methylation

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.

Feb 24, 2021

Cell Studies on SARS-CoV-2 Spike Variant, Host Transcriptomes, Glioma-Infiltrating T Cells

In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.

Feb 24, 2021

Glaucoma GWAS Meta-Analysis Uncovers New Risk Loci, Shared Risk Across Ancestry Groups

Investigators detected more than 100 risk loci for primary open-angle glaucoma, with mostly similar effects in people with European, Asian, or African ancestry.

Feb 23, 2021

SARS-CoV-2 Test Pooling Studies Offer Insights for Implementing, Optimizing Approaches

A pair of studies published this week present an analysis of a real, large-scale testing pooling effort as well as analyses of how to further improve such strategies.

Feb 23, 2021

PNAS Papers on Breast Cancer Immunotherapy, Histone Mutations, Mosquito Mapping

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.

Feb 16, 2021

PNAS Papers on Single-Cell SNV Detection, Bone Healing-Related Immune Features, More

In PNAS this week: single-cell whole-genome amplification approach for SNV detection, immune features linked to bone regeneration, and more.

Feb 11, 2021

Genetics of Afternoon Snoozes

A new genome-wide association study in Nature Communications uncovers five dozen loci linked to frequency of afternoon naps.

Feb 09, 2021

From Water and Fins to Land and Legs

The Economist reports that a single genetic change could have enabled vertebrates to leave the water.

Feb 08, 2021

Disease-Linked Mutations May Affect Protein-Protein Interactions, Influence Drug Response

Both germline variants and somatic tumor variants linked to disease are more likely to disrupt protein-protein interactions than other variants.

Feb 03, 2021

Single-Nucleus Sequencing Holds High Risk, High Reward for Translational Transcriptomics

Premium

As researchers embrace single-nucleus analysis to probe previously intractable tissues, companies are trying to deliver more reliable sample preparation.

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The Scan

P.1 Re-infection Concerns

New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.

Aiming for May

According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.

NIH Program to Address Structural Racism

The US National Institutes of Health has a new initiative to address structural racism in biomedical research.

PNAS Papers on Myelopathy GWAS in Japan, Hypertrophic Cardiomyopathy, MRSA Methylation

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.

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