Harvard | GenomeWeb


The startup, which was founded by Harvard's George Church, plans to commercialize a sequencing technology that is also able to map RNAs in 3D. 

Researchers are making mutations in a cell's genome to mark it and later read out that information to create cell lineage maps and chemical interaction histories.

By focusing on sequences that have diverged rapidly in humans, researchers identified regulatory sequences suspected of affecting neural processes.

Genome sequences of individuals from populations around the world provided insights into out-of-Africa migrations and Aboriginal Australian ancestry.

A commentary in NEJM argues that precision medicine will require clinicians and patients to be more comfortable with risk and probability.

Diversity Needed

Genetic testing may have misdiagnosed African Americans with hypertrophic cardiomyopathy, a New England Journal of Medicine study says.

By comparing pre-treatment and post-relapse samples from vemurafenib-treated melanoma patients, researchers uncovered resistance-related cohesin complex mutations.

A pair of Harvard Medical School researchers finds that pediatric clinical trials are often stopped early and sometimes never published.

A high risk score was associated with worse memory, smaller hippocampi, and cognitive decline, and could be used to detect disease prior to the onset of symptoms.

Evotec may use the technology for its drug-development and R&D activities, including in the development of research tools and in target identification.


In Nucleic Acids Research this week: ProTraits includes genetic, phenotypic data on bacteria, archaea; Candida albicans assembly 22; and more.

The Wall Street Journal reports that researchers are looking beyond Cas9 for CRISPR editing.

Familial DNA searches in criminal cases are winning over some critics, the Los Angeles Times reports.

In PNAS this week: miR-515 levels higher in women with preeclampsia, horizontal gene transfer in parasitic plants, and more.