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In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.

In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.

Investigators detected more than 100 risk loci for primary open-angle glaucoma, with mostly similar effects in people with European, Asian, or African ancestry.

A pair of studies published this week present an analysis of a real, large-scale testing pooling effort as well as analyses of how to further improve such strategies.

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.

In PNAS this week: single-cell whole-genome amplification approach for SNV detection, immune features linked to bone regeneration, and more.

A new genome-wide association study in Nature Communications uncovers five dozen loci linked to frequency of afternoon naps.

The Economist reports that a single genetic change could have enabled vertebrates to leave the water.

Both germline variants and somatic tumor variants linked to disease are more likely to disrupt protein-protein interactions than other variants.

As researchers embrace single-nucleus analysis to probe previously intractable tissues, companies are trying to deliver more reliable sample preparation.

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New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.

According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.

The US National Institutes of Health has a new initiative to address structural racism in biomedical research.

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.