GIS

The Genome Institute of Singapore will collaborate with the new center to develop applications related to cancer diagnosis and treatment stratification.

Using brain samples from individuals with or without autism spectrum disorder, researchers identified H3K27ac histone acetylation marks associated with ASD.

The partners will focus on sequencing and analyzing bacteria and viruses that cause a number of diseases as well as those that make up human microbiomes.

The researchers used a method known as paired-end tag sequencing, or DNA-PET, to identify five recurrent gene fusions in Asian populations with gastric cancer.

The partners will use Pyrobett's technology to develop molecular diagnostics for bacterial and viral genotyping and cancer mutation detection.

The software sifts through multiple omics datasets to better identify candidate mutations likely play a role in tumor development and survival.

NEW YORK (GenomeWeb) – Through a genome-wide association study, an international team of researchers has identified a variant linked with resistance to typhoid fever.

NEW YORK (GenomeWeb) – Researchers from the Genome Institute of Singapore have applied a ChIP-seq method that works on small amounts of input DNA to study epigenetic changes in gastric cancer, identifying hundreds of somatically altered promoters and predicted enhancers, many of which have previo

NEW YORK (GenomeWeb News) – The Prolaris laboratory of the Genome Institute of Singapore said today that it has received Illumina certified service provider certification for sequencing using Illumina's products.

Sequencing-based strategies are at the heart of several recent studies by researchers set on surveying RNA secondary structure profiles in a given organism or cell type, adding to the structural data that can be obtained by more targeted but time-consuming methods.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.