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George Mason University

The partners will work together on personalized medicine research at several new centers in the Northern Virginia area.

NEW YORK (GenomeWeb) – The Translational Genomics Research Institute and George Mason University today said that they will integrate genomics, proteomics, and molecular profiling in an alliance aimed at finding personalized treatments for patients.

NEW YORK (GenomeWeb News) – Researchers from China and the US will sequence 100 human adenoviruses, including ones that cause respiratory, gastrointestinal, and ocular diseases, under a partnership announced today.

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Callida Genomics, Illumina, SRU Biosystems, George Mason University, Receptors, TessArae, Affymetrix

With diagnostic development shifting from single-marker to multi-marker tests, multiple-reaction monitoring mass spectrometry has emerged as a potentially valuable clinical tool. Further improvements in the platform's cost and variability are needed, however, to make it competitive with immunoassays.

Technology developed by Lance Liotta and Emanuel Petricoin will be used to find and identify biomarkers for evaluating new investigational therapies for the neoadjuvant-drug study.

The collaborations center on targeted single-reaction monitoring-based workflows that Thermo Fisher's Biomarker Research Initiatives in Mass Spectrometry Center has been developing to allow rapid development of mass spec-based assays and cross-validation of biomarkers across different laboratories.

Thermo has expanded its collaboration with university partners, including George Mason's Lance Liotta and Emanuel Petricoin, to verify and validate protein biomarkers for cancer and other diseases.

The trial is using technologies from Caris Life Sciences and George Mason University's Center for Applied Proteomics and Molecular Medicine to create proteomic profiles to determine which therapies work best for each individual patient.

If the researchers are successful, GMU's Emanuel Petricoin believes it could lead to the development of the first ever protein activation companion assay.

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