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Tumor microenvironment cell transcriptomes pointed to four stromal cell clusters, including immune interacting support cells predicted to impact immunotherapy response.
The collection of more than 125,000 exomes and 15,000 genomes has enabled an analysis of loss-of-function variants, may help diagnose rare disease, and guide drug development.
The Medical Genome Reference Bank, which currently holds data for more than 2,500 healthy elderly Australians, could help scientists understand the genetics of healthy aging.
By combining mitochondrial DNA and climatic data, an international team of researchers found that an early mitochondrial lineage emerged in a paleo-wetland.
Australian Clinical Labs will take over the the clinical pathology and reporting responsibilities of Garvan Institute of Medical Research subsidiary Genome.One.
An Australian team has sequenced some 4,000 healthy individuals over 70 years old for the Medical Genome Reference Bank database.
The new hardware expands Garvan's current system so that it can better support large-scale whole-genome and single-cell sequencing initiatives.
It will be possible to upload genomic data to Australia's My Health Record system, which has raised privacy issues, the Sydney Morning Herald reports.
The Garvan team has shown that whole-genome sequencing can diagnose more cases than targeted panels and is now demonstrating its cost-effectiveness.
With the new five-year funding, patients across Australia with rare or less common cancers will be able to access the program through a network of eight cancer centers.
President Donald Trump might not approve the stricter standards the US Food and Drug Administration is developing for authorizing a SARS-CoV-2 vaccine, according to Politico.
Wired reports that Oxitec has now developed a genetically modified fall armyworm.
A large genetic study finds SARS-CoV-2 viruses with a certain variant are spreading more than others, according to the Washington Post.
In Nature this week: sister-chromatid-sensitive chromosome conformation capture approach, and more.