Fred Hutchinson Cancer Research Center Study Identifies Gene Variants Associated With Aggressive Prostate Cancer Premium Exome sequencing of more than 17,000 men with prostate cancer identified known and novel gene variants linked to risk of aggressive disease. Study Explores Role of Prostate Cancer Mutations in 3' Untranslated Regions Researchers at Fred Hutch used massively parallel reporter assays and CRISPR base editing to understand the impact of 3'UTR somatic mutations in prostate cancer. Esophageal Cancer, Precancer Study Points to Extrachromosomal DNA Appearance By analyzing precancerous Barrett's esophagus samples, researchers found that oncogene-containing extrachromosomal DNA may contribute to cancer transformation. Multiomic Study Points to New Colorectal Cancer Risk Contributors Researchers tracked down more than 100 new risk variants with a combination of genomic, transcriptomic, and methylation analyses, highlighting new and known risk pathways. Breast, Ovarian Cancer Study Finds Ties Between Types of BRCA Alterations, Treatment Response Breast and ovarian cancers with BRCA1 promoter methylation changes showed poorer chemotherapy responses than those with genetic alterations in BRCA1 or BRCA2. May 19, 2022 CellCarta Acquires Rights to Targeted Protein Assays from Fred Hutch Spinout Precision Assays Dec 15, 2021 EpiCypher Licenses Chromatin Profiling Technologies From Fred Hutchinson Cancer Center Sep 23, 2021 Machine Learning Method Allows Highly Multiplexed Cell Surface Protein Analysis via Flow Cytometry Premium Apr 21, 2021 Red Blood Cell Traits Linked to New Loci With Whole-Genome Sequencing Data Jan 6, 2021 TwinStrand Biosciences Explores Error Reduction Sequencing Tech in Various Applications Premium Nov 25, 2020 Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers Nov 11, 2020 Adaptive Biotechnologies Prepares to Launch T Cell-Based COVID-19 Test Premium Sep 11, 2020 Genomic Epidemiology Studies Retrace Sources of Early SARS-CoV-2 Outbreaks in US, Europe Apr 13, 2020 SARS-CoV-2 Genomes Let Researchers Retrace Viral Spread, Mitigation Effects Apr 7, 2020 Multiomic Approach Measures Protein Expression, RNA Transcript Levels of Single Cells Feb 20, 2020 Lucid Diagnostics, Fred Hutchinson Cancer Research Center Ink Esophageal Cancer Biomarker Deal Oct 10, 2019 Mission Bio Lands $2M NCI SBIR Grant to Advance Minimal Residual Disease Detection Oct 2, 2019 SEngine Precision Medicine Raises $5.1M in Series A Financing Jul 18, 2019 Immune Response Dampened in Many Cancers by Reactivation of Embryonic Gene May 30, 2019 New Studies Examine Genetic, Environmental Risk Factors Linked to Lung Cancer Among Never Smokers Premium May 9, 2019 Broad Aims for Portable Pipeline as It Readies AWS-Compatible Version of Cromwell Premium Apr 4, 2019 Epigenetic Therapies May Prime Tumors to Better Respond to Other Treatments, AACR Speakers Say Dec 3, 2018 Colorectal Cancer Risk Linked to Common, Rare Variants Nov 9, 2018 National Cancer Institute Awards $4M to Brain Tumor Sequencing Projects Nov 6, 2018 BGI, Fred Hutchinson Sign Collaboration MOU Load More Breaking News Rare Kidney Cancer Genomic Analysis Reveals Potential Target, Suggests Treatment SEC Concludes CareDx Investigation, Recommends No Enforcement Action Streck Quality Controls for DiaSorin's Luminex Sepsis Tests Receive FDA Clearance Adela Closes $48M Financing to Develop Cancer Monitoring, Early Detection Test 3EO Health At-Home Molecular COVID-19 Test Nabs FDA EUA The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.