Re-expression of DUX4, which is normally silenced in somatic tissues, appeared to stymie MHC class I-related immune activity in several solid cancer types.
Following an April hackathon and work from Melbourne Genomics and Fred Hutch, the Broad is about to release a long-awaited AWS version of its Cromwell workflow engine.
Clinical trials investigating whether epigenetic treatment can restore susceptibility to other treatments are underway in colorectal, lung, and breast cancers.
Researchers identified 40 new and 55 known risk variants using a GWAS meta-analysis that included low-frequency variants gleaned from genome sequence data.
The partners said they have agreed to work together on projects in a range of diseases, as well as establish research alliances with groups in China and Africa.
In PLOS this week: statistical approach for finding somatic mutation-based associations, genomic and methylomic patterns in virulent and non-virulent forms of a swine respiratory pathogen, and more.
In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.
