Clinical trials investigating whether epigenetic treatment can restore susceptibility to other treatments are underway in colorectal, lung, and breast cancers.
Researchers identified 40 new and 55 known risk variants using a GWAS meta-analysis that included low-frequency variants gleaned from genome sequence data.
The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.
The partners said they have agreed to work together on projects in a range of diseases, as well as establish research alliances with groups in China and Africa.
In PLOS this week: statistical approach for finding somatic mutation-based associations, genomic and methylomic patterns in virulent and non-virulent forms of a swine respiratory pathogen, and more.
In PNAS this week: history and genetic diversity of the scarlet macaw, approach for predicting human flu virus evolution, and more.
In PNAS this week: pan-cancer analysis of Fbw7 mutations, COBASI approach to find single-nucleotide variants, and more.
Smithsonian reports that some researchers are turning to gene editing to target established infections like herpes.
The institute is being funded with a gift from the family of recently deceased Costco Cofounder Jeff Brotman, and will be directed by UW's Jay Shendure.
The company combines screening of live, patient-derived tumor cells with DNA sequencing and data analysis to match individuals with optimal drug therapies.
Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.
St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.
St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.
In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.