Francis Crick Institute
Broken String Biosciences, Crick Institute Team up for ALS Research
The partnership is being conducted through the Crick Institute's business engagement fund, a new initiative supported by the UK's Medical Research Council.
Viral Transmission Study Sees Signs of Extensive Human-to-Animal Spread
Using sequence data, researchers find viruses can jump between humans and animals, and vice versa, with those with broad host ranges more likely to make a swap.
Ancient DNA Analysis Uncovers Cases of Trisomy
Researchers found six Down syndrome cases and one case of Edwards syndrome through screening almost 10,000 ancient samples, all buried at a young age.
Congenital Heart Defect Features of Down Syndrome Spelled Out with Transcriptomics, Mouse Models
Increased DYRK1A gene dosage led to altered expression of mitochondrial and cell proliferation genes in developing cardiac muscle cells, while DYRK1A inhibitors restored activity.
Study Examines Cross-Species Sex-Biased Expression at Gene, Organ Levels
Researchers traced sex-biased gene expression patterns across different developmental stages in five organ types from half a dozen species.