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The team used this system to perform orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs.

Speakers at this year's ABRF meeting described how they used single-cell tools in combination with other single-cell approaches and other methods.

ETH Zurich has moved to dismiss a professor accused of bullying, according to ScienceInsider.

In PNAS this week: whole genome and population genetic analysis of two aspen species, signatures of circulating hepatocellular carcinoma tumor DNA, and more.

Researchers have found genomic, transcriptomic, proteomic, and phenotypic variation in a comparison of HeLa cells across laboratories and over time.

Store It All as DNA

Researchers in Switzerland are investigating using DNA as a data-storage device.

A method developed at MIT creates polyacrylamide beads around droplets containing single cells to sequester bacterial genomes and allow for harsh lysis conditions; it then uses concatenated PCR and sequencing to address links between phylogeny and function.

The technique has the promise of enabling basic cancer research, and could also be used for in vitro screening of chemotherapeutic drug response.

NEW YORK(GenomeWeb News) – The University of Perugia's Agostinho Carvalho and colleagues explored the influence that polymorphisms in a gene called PTX3 — known for its role in mediating immune responses to fungi — might have on an individual's risk of developing invasive aspergillosis infections

NEW YORK (GenomeWeb News) – Researchers at the Swiss Federal Institute of Technology have developed a tool to single out specific proteins contained within the Mycobacterium tuberculosis proteome.

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At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.

Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.

In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.