ETHZ

Store It All as DNA

Researchers in Switzerland are investigating using DNA as a data-storage device.

A method developed at MIT creates polyacrylamide beads around droplets containing single cells to sequester bacterial genomes and allow for harsh lysis conditions; it then uses concatenated PCR and sequencing to address links between phylogeny and function.

The technique has the promise of enabling basic cancer research, and could also be used for in vitro screening of chemotherapeutic drug response.

NEW YORK(GenomeWeb News) – The University of Perugia's Agostinho Carvalho and colleagues explored the influence that polymorphisms in a gene called PTX3 — known for its role in mediating immune responses to fungi — might have on an individual's risk of developing invasive aspergillosis infections

NEW YORK (GenomeWeb News) – Researchers at the Swiss Federal Institute of Technology have developed a tool to single out specific proteins contained within the Mycobacterium tuberculosis proteome.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Swiss proteomics firm Biognosys has raised CHF2.7 million ($3 million) in a Series A round, it announced on Monday.

The project will involve several sequencing technologies, including Pacific Biosciences' PacBio RS.

By looking at microRNA profiles in two mouse models of obesity, researchers have identified a pair of closely related miRNAs that are involved in regulating glucose metabolism and insulin signaling.

Pages

A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.

A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.