A UK research team performed single-cell RNA sequencing on epiblast cells to learn more about how gene expression directs organ formation.
While shotgun mass spec experiments are able to identify on the order of 13,000 proteins, an average of 75 percent of spectra generated are never identified.
Sanger Institute researchers analyzed the genomes and mutational signatures of 560 breast cancer tumors, identifying new ways to classify the disease.
Questions remain about how the €6.7 billion ($7.6 billion) pledged for the implementation of the European Open Science Cloud over the next four years will be spent.
Researchers used the computational method to identify T cell clonotypes in a mouse Salmonella infection model.
The scientists used a multi-omics approach to determine that organs don't age in the same ways or at the same pace.
EMBL-EBI's Oliver Stegle is taking a statistical approach to understanding genotype-phenotype associations.
New analytical approaches combine single-cell RNA-seq profiles with in situ gene expression markers to place sequenced cells in a spatial context.
The consortium currently has phenotype data for more than 1,100 mouse knockout strains and hopes to have as many as 5,000 by next year
The awards are for data infrastructure projects to support research in agricultural plant and animal genomics.
In Science this week: metagenomic-based technique for determining protein structure, and more.
An academic laments the rise of narcissism in the sciences, the Guardian reports.
Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.
The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.