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Leukemia Subclones, Treatment Targets Spelled Out in Single-Cell Multiomics Study
Researchers teased out structural variants, intratumoral heterogeneity, and tumor subclone evolution in complex karyotype acute myeloid leukemia.
Chemically Induced Bladder Cancer Risk Influenced by Gut Microbe Metabolism, Study Finds
Researchers identified gut microbial species involved in metabolizing a carcinogen linked to bladder cancer formation in a mouse model.
Long-Read Nanopore Sequencing Boosts Structural Variant Analysis in 1000 Genomes Project Dataset
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Two research teams have been reanalyzing 1000 Genomes Project samples with nanopore long reads to build a more comprehensive variant catalog.
Medulloblastoma Long-Read Sequences Reveal Complex Rearrangements, Methylation Changes
With Oxford Nanopore sequencing, researchers found DNA methylation clues and complex rearrangement patterns that were subsequently assessed in a broader cancer set.
Researchers paired a modified 10x Genomics single-cell library preparation protocol with a Bayesian model to infer relationships between cells based on mutations.
Aug 31, 2020
New Initiative Aims to Build Organoid Cell Atlas
May 12, 2020
Mar 11, 2019
Jun 21, 2018