Duke

A multi-region analysis of colorectal cancers suggests samples from opposite sides of a tumor can help trace early, invasiveness-related tumor characteristics.

Speakers at HudsonAlpha's Genomic Medicine Conference said while sequencing results sometimes result in a diagnosis and change in care, they often have no consequence.

Researchers are exploring alternative ways to return genetic testing results to grapple with the anticipated increase in testing and see a role for the web.

Three-month-old health data integrator Datavant hopes its analytics technology can improve the speed and success of clinical trials.

This Week in Science

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

A lawyer and a scientist say the best result in the CRISPR patent fight would be narrow patents that prevent anyone from controlling downstream innovation.

In Genome Research this week: approach for profiling complex genomic rearrangements, sex-biased microRNA expression, and more.

Using sequences from hepatocellular carcinomas in Asia, researchers identified numerous cases with mutation signatures linked to aristolochic acid exposure.

Durio zibethinus

Using new genome and transcriptome sequences, researchers saw expansions and expression jumps in sulfur and fruit ripening pathways in Durio zibethinus.

This Week in PNAS

In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.

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Science speaks with the University of Michigan's Jedidiah Carlson, who has tracked population genetic discussions at white nationalist sites.

Gene therapies could qualify for a faster US Food and Drug Administration approval process, according to Stat News.

NPR reports that the US House of Representatives has passed a bill to enable terminally ill patients access to experimental drugs.

In Genome Research this week: inversion variants mapped in human, non-human primate genomes; transcriptome profiling of maize, sorghum; and more.