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Leukemia Subclones, Treatment Targets Spelled Out in Single-Cell Multiomics Study
Researchers teased out structural variants, intratumoral heterogeneity, and tumor subclone evolution in complex karyotype acute myeloid leukemia.
In an indirect comparison study by researchers in Germany, a fecal immunochemical test showed similar sensitivity and specificity as Exact Sciences' Cologuard Plus test.
Called optiPRM, the approach could help detect cancer neoantigens in patient tumor samples for applications like the development of personalized cancer vaccines.
German Children's Cancer Center Aims to Expand Global Access to Methylation-Based Tumor Classifier
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The program will provide funding and expertise to clinics in low-income countries to run methylation array-based assays to classify central nervous system tumors in children.
Mutational Signatures Profiled in Pediatric Cancers
Researchers uncovered and analyzed mutational signatures in 27 cancer types or subtypes by analyzing genome sequences for nearly 800 tumors.