Dana-Farber

Shared gastric adenocarcinoma tumor features seem to span geography and ethnicity, despite shifts in the proportion of tumors from different molecular subtypes.

One speaker cited the success of screening Ashkenazi Jewish women for BRCA mutations, but another said extending testing to a wider population could be harder.

The developers said such a signature could help triage people exposed to radiation through war, a terrorist attack, or an industrial accident.

Researchers identified mutations present prior to allogeneic hematopoietic stem cell transplantation that coincided with MDS survival and relapse.

Alterations to Target

Researchers find that genetic testing of pediatric brain cancer can uncover clinically relevant alterations, Technology Review reports.

The results of the Harvard-led study suggest that the immune system struggles to infiltrate and attack tumors with more aneuploidy.

The study showed that targeted sequencing was feasible, identified many clinically relevant alterations, and directed effective targeted therapy in several cases.

The study also found that esophageal squamous cell carcinomas resemble head and neck cancer, while esophageal adenocarcinomas are similar to gastric cancers.

San Antonio River Walk

Using sequencing approaches, researchers are learning more about what drives breast cancer metastasis and resistance.

The partners aim to create a broad collection of high-quality genomic and clinical data from multiple myeloma patients to improve disease diagnosis, prognosis, and treatment.

Pages

Researchers suggest that genetic variations could influence the side effects people experience when using synthetic cannabinoids, the International Business Times reports.

An analysis has examined the makeup of researchers on Twitter and what they share, Nature News reports.

At Stat News, Jim Kozubek argues that the Broad Institute is pushing the boundary of what a nonprofit is.

In PNAS this week: gut microbes may affect honeybee weight, phenotype and gene expression changes in DiGeorge syndrome, and more.