Dana-Farber Nature Papers Examine Gene Expression Across Land Plants, Tumor Cell Response to Natural Killer Cells In Nature this week: a comparison of land plant gene expression atlases, and more. CRISPR-Cas9 Genome Editing Can Lead to Extensive Chromosome Rearrangements A study showed that chromothripsis, a mutational process that can lead to congenital disease and cancer, can result from on-target editing with Cas9. Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry While risky variants in the FH gene were more common in renal cell carcinoma patients with African ancestry, European patients more often carried pathogenic CHEK2 gene changes. Nonprofit Count Me In to Return Genomic Results to Patients With Rare Cancers Premium With a new $16 million NCI grant, Count Me In is working with the Broad and Dana-Farber to engage osteosarcoma and leiomyosarcoma patients in their own care and in research. Cell Studies on SARS-CoV-2 Spike Variant, Host Transcriptomes, Glioma-Infiltrating T Cells In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more. Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Sep 3, 2020 Blood Cell Traits Linked to Individual Loci, Polygenic Contributors in International Studies Aug 10, 2020 T Cell Receptor Repertoire Linked to Anti-PD-1 Therapy Response in Hodgkin Lymphoma Aug 4, 2020 BostonGene Partners With Dana-Farber's Weinstock Lab on T-Cell Lymphoma Biomarker Research Jul 24, 2020 MMRF to Integrate New NGS Liquid Biopsy Platform With Myeloma Patient Online Registry Premium Jul 20, 2020 Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift Jul 13, 2020 Pediatric Ependymoma Single-Cell Analysis Points to Signatures Linked to Outcomes Jun 26, 2020 Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method Premium Jun 26, 2020 Dana-Farber Team Reports Progress With Precision Oncology Trial Matching Software Jun 23, 2020 Tissue Network Analysis Points to Significant Sex-Related Regulatory Differences Jun 15, 2020 Homomorphic Encryption Might Hold Key to Fast, Large-Scale GWAS Premium Jun 4, 2020 Studies Show Potential of Video, Online Education to Expand Cancer Risk Genetic Test Access Premium Apr 29, 2020 IntegraGen Receives CE Mark, Installs Software at Dana-Farber Cancer Institute Premium Apr 28, 2020 Immune Cell Shifts Mark Microenvironments of Precursor Cases Progressing to Multiple Myeloma Apr 22, 2020 Pancreatic Cancer Clinical Risk Prediction Appears to Improve With Genetic, Biomarker Data Apr 15, 2020 Glioma Hypermutation May Not Correspond to Checkpoint Immunotherapy Response, Study Suggests Apr 8, 2020 Tens of Thousands of Protein-Protein Interactions Reported in Human Reference Interactome Map Apr 8, 2020 Esophageal Cancer Case Study Suggests Utility as Clinicians Explore Expanded Uses for Liquid Biopsy Premium Mar 31, 2020 Grail Multi-Cancer Test Meets Validation Goals; Patients to Receive Results Under New Pilot Premium Mar 23, 2020 Lung Cancer Brain Metastasis Genomes Marked by Recurrent Amplifications, Deletions Load More Breaking News Beckman Coulter, Invitae Partner to Develop NGS Library Prep Applications Sick Infants Profiled with WGS See Better Diagnosis, More Care Changes UC Santa Cruz Center for Live Cell Genomics Wins $13.5M NIH Grant Genetron Health, Impact Therapeutics Partner for Anti-Cancer Drug, CDx Development Canaccord Genuity Initiates Coverage of Pacific Biosciences With Buy Rating Alternative Genetic Counseling Approach Leads to Higher Patient Satisfaction, Study Suggests The Scan Highly Similar Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News. Gain of Oversight According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research. Lasker for mRNA Vaccine Work The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.