CSHL
New Resource Combines Functional Genomics, Diploid Genomes for Variant Annotation
Coupling high-quality, long-read genomes with functional assays, researchers tracked the effects of genetic variants across dozens of tissue types in four individuals.
Glioblastoma With Wild-Type TP53 Linked to Potentially Targetable Epigenetic Alteration
With the help of a CRISPR-based screen, researchers linked enhanced activity by the chromatin regulatory gene BRD8 to altered p53 function in cells containing wild-type TP53.
The method, which incorporates a background reduction step into the existing approach, reported higher on-target sequencing depth and end-to-end read length.
Veranome, Cold Spring Harbor to Develop In Situ Sequencing Technologies
The collaboration aims to expand Veranome's spatial transcriptomics portfolio with in situ neural mapping, among other applications.
Some are comparing iGenomics, a former high school intern's creation, to the fictional "medical tricorder" of "Star Trek" fame.