CSHL Glioblastoma With Wild-Type TP53 Linked to Potentially Targetable Epigenetic Alteration With the help of a CRISPR-based screen, researchers linked enhanced activity by the chromatin regulatory gene BRD8 to altered p53 function in cells containing wild-type TP53. New Cas9 Enrichment Method Improves Targeted Nanopore Sequencing Premium The method, which incorporates a background reduction step into the existing approach, reported higher on-target sequencing depth and end-to-end read length. Veranome, Cold Spring Harbor to Develop In Situ Sequencing Technologies The collaboration aims to expand Veranome's spatial transcriptomics portfolio with in situ neural mapping, among other applications. Cold Spring Harbor Lab Develops iPhone App for Mobile Sequencing Analysis Premium Some are comparing iGenomics, a former high school intern's creation, to the fictional "medical tricorder" of "Star Trek" fame. NYGC Initiative Receives up to $2.1M for Cancer Studies in Ethnic Minorities The funding is being provided under the NYGC's Polyethnic-1000 initiative, which was launched in 2018 to study cancer care inequities in underserved populations. Aug 6, 2020 Algorithm Points to Complex Hominin Mixing History Jun 17, 2020 Tomato Structural Variations Linked to Gene Expression, Traits Apr 21, 2020 Envisagenics to Bring RNA Splicing Software Platform to J&J Lung Cancer Initiative Jul 3, 2019 UC Irvine-Led Team Wins $4M Chan Zuckerberg Initiative Grant for Breast Cell Atlas Jan 16, 2019 Rapid Nanopore Sequencing of 100 Tomato Genomes Enables Structural Variant Analysis Dec 18, 2018 Cancer Genetic Studies Explore Prognostic Value of Copy Number Alterations, Other Biomarkers Premium Dec 5, 2018 Chan Zuckerberg Initiative Awards $52M in Grants for Neurodegenerative Disease Research Jul 24, 2018 NY Genome Center Wins $1M Grant to Study Cancer Genetics Diversity May 22, 2018 Envisagenics Wins $1.5M NIH Grant to Advance Alternative Splicing Analysis Tech May 10, 2018 RNA, Chromatin Interaction Mapping Approach Presented at Biology of Genomes Mar 28, 2018 Single-Cell Sequencing Strategies Trace Zebrafish Cell Lineages, Mouse Brain Connections Feb 6, 2018 Autism Analysis Uncovers Ties Between Motor Skills, Damaging De Novo Mutations Oct 24, 2017 NIH Announces BRAIN Initiative Grants for 2017 Sep 22, 2017 Cold Spring Harbor Team to Use $2.7M NIH Grant to Map Long Range Neural Projections Premium Jul 20, 2017 Researchers Design, Construct Genome-Wide Sequence-Verified Arrayed CRISPR Library May 11, 2017 Researchers Use New Approach to Uncover Variants Affecting Longevity in Humans May 10, 2017 Genomic Autopsies Offer Diagnoses in Study of Perinatal Death Cases Aug 22, 2016 CSHL Genome Engineering Meeting Shows Maturing CRISPR Technologies Jun 24, 2016 RNA Sequencing Uncovers Complex Maize Transcriptome May 16, 2016 WUSTL's Mardis Discusses Cancer Vaccine Work at Biology of Genomes Meeting Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.