Critical Path Institute

The agreement is part of a larger effort by the company to apply its Signabody affinity reagents to toxicity biomarker work and other areas of drug development.

The partners aim to sequence thousands of tuberculosis bacteria isolates as part of a broader effort to develop personalized treatments for the disease.

The database of genotype, phenotype, and clinical data from multi-drug resistant TB cases may support improved diagnostic development and clinical decision making.

The data repository of tuberculosis drug susceptibility will spur diagnostic assay development; access will be open to partner firms in one year. 

NEW YORK (GenomeWeb News) – Certara said this week that it is working with the Critical Path Institute, C-Path, to create a physiologically-based pharmacokinetic model of the human lung using Certara's Simcyp Population-based simulator software that will be used to test new tuberculosis drugs.

Matthias Mann, director of the Max Planck Institute of Biochemistry, has been awarded the 2012 Louis-Jeantet Prize for Medicine and the 2012 Ernst Schering Prize for his work developing mass spectrometry procedures for protein analysis and methods for large-scale proteomics.

Life Technologies VP of Research and Development Manohar Furtado has been appointed to serve as an advisor on the National Biodefense Science Board, a federal advisory committee for the Department of Health and Human Services.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.