Critical Path Institute

The database of genotype, phenotype, and clinical data from multi-drug resistant TB cases may support improved diagnostic development and clinical decision making.

The data repository of tuberculosis drug susceptibility will spur diagnostic assay development; access will be open to partner firms in one year. 

NEW YORK (GenomeWeb News) – Certara said this week that it is working with the Critical Path Institute, C-Path, to create a physiologically-based pharmacokinetic model of the human lung using Certara's Simcyp Population-based simulator software that will be used to test new tuberculosis drugs.

Matthias Mann, director of the Max Planck Institute of Biochemistry, has been awarded the 2012 Louis-Jeantet Prize for Medicine and the 2012 Ernst Schering Prize for his work developing mass spectrometry procedures for protein analysis and methods for large-scale proteomics.

Life Technologies VP of Research and Development Manohar Furtado has been appointed to serve as an advisor on the National Biodefense Science Board, a federal advisory committee for the Department of Health and Human Services.

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Led by the Critical Path Institute and Roche's Ventana Medical Systems, the project aims to fill a gap in the current biomarker pipeline, and will hopefully speed the progression of proposed biomarkers through the FDA's qualification pipeline, said a C-Path official.

Critical Path Institute and Roche's Ventana Medical Systems will lead the effort to develop the lab, which aims to advance personalized medicine in the Grand Canyon State by developing standards and best practices for accurately identifying biomarkers of patients.

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Vivek Murthy is no longer the surgeon general of the US, the Associated Press reports.

Parents who learn of their increased genetic risk of disease also contend with telling their children about theirs, the New York Times writes.

In PLOS this week: loci linked to body mass index measurements, long non-coding RNA expression and urothelial carcinoma prognosis, and more.

Mary Beckerle has been removed as director of the Huntsman Cancer Institute in what one researcher refers to as a "coup," ScienceInsider reports.